Protein Alignment CG1371 and nra-4

DIOPT Version :9

• Sequence 1: NP_610551.1
• Gene: CG1371 / 36053
• FlyBaseID: FBgn0033482
• Length: 1199
• Species: Drosophila melanogaster
• Sequence 2: NP_872191.1
• Gene: nra-4 / 3565008
• WormBaseID: WBGene00015344
• Length: 1123
• Species: Caenorhabditis elegans
• Alignment Length: 1217
• Identity: 323/1217 - (26%)
• Similarity: 554/1217 - (45%)
• Gaps: 160/1217 - (13%)

  Fly     9 VILLIKLFQNANAGEVEVVGCGGFIKSHAEIDFS--RVEIKLLTKQGSLKDKTDCSPSNGYYFLP 71
            :|||..|...|.|   .|..|.|.:||.:.:|:|  :::::|||.:|.:|.:.:.:|||||:.:|
 Worm     6 LILLSLLLPGALA---NVYSCAGSVKSTSPVDYSQLKLQVRLLTLEGHMKHEEEVNPSNGYFMIP 67

  Fly    72 IYDKGDYLLSISPPPGWSFEPEQVELNFDGKTDVCSQGRDVNFVFKGFGITGQVALAAGGGARGV 136
            :|:||.|.|.:|.|.|:.|||:.:|:..|||||.||...|:.|...||.:.|.|    .|.|.|:
 Worm    68 VYNKGHYTLKVSAPAGYYFEPDSIEIKIDGKTDACSLNEDLVFHLTGFSVRGTV----DGAAAGL 128

  Fly   137 DVELRSEQGEVRRTKSDANGVFSF-TPIIPGNYVVK-ASHARWHFSKAEHKV------VVVSGNT 193
            .:.|.....::..||::..|.:.. .|  ||.|.|. .:.|....||.:..|      |||:.|.
 Worm   129 PLVLTENGKQIAETKTEDGGKYEMRAP--PGKYEVSTGAGASECISKGKTSVEVKNAPVVVTPNF 191

  Fly   194 ELPANSLVVSGF--DVVGRFDSSSPLPGNLGVALYKKKGQSLVPKCETSSPAPPN--------SV 248
            :       :||:  :|..|.:|.:|....: :.||           .|||...||        |:
 Worm   192 K-------ISGYQLEVHTRTESMNPFVDAV-MTLY-----------ATSSIDLPNIKCVGSEGSL 237

  Fly   249 NSAYESASSC-FSQLDKSGEYIFKNVPSGKYLLQAINLDSKLKLHLSPELLELEVGKDTLQIKDE 312
            |........| ..:.|..|......||||:|.|.|.:::....::.||...::.|.    |...|
 Worm   238 NVPSTHNVKCSIGKTDPRGRLSVACVPSGEYYLAASHVNGPKSINFSPNPQKVVVS----QAASE 298

  Fly   313 FKITGFTVSGRVLTSAGGEPLKSAVIKVNGKKVAETDAQGSYTLENLKAGT-VNIEVESSQLQFS 376
            .:....:.:|||..::...||....:.||.|...:||:||...:||||... ..|..::...|||
 Worm   299 ARFVAQSATGRVRVTSKDLPLSGVEVLVNEKSGGKTDSQGYLKIENLKEDEHTTITAKAPNTQFS 363

  Fly   377 PLQVKAQINTASLPTIVPSAYEVCGKVVSPKSHNVGLTKIGSTF------HSSASTNAETGNWCA 435
            .:....:.....:..:....:::||:|  .||.|..|.|:  ||      .|........|::|.
 Worm   364 TVHANVKFPKVEIQDVTVQKFDICGQV--EKSENGVLGKL--TFTRKDDKRSLEIQPKADGSFCQ 424

  Fly   436 FLPVGKYTIEVLTTDADKAAGVQFFPVQQQTEVRDAPVNGITFSQLRAKIRGELQCLPDATATCT 500
            .:..|.:|||    ..||.:.:.  |...:.||....|..:.|:..:......|.|:    ..|.
 Worm   425 PVSPGLFTIE----PTDKTSSLT--PRLLEVEVLKNAVTNLRFTHFKTNANVHLSCI----GACP 479

  Fly   501 SAEVTL----QALDATGQPTENKWKARAHRGK--YVFKDMLPGPYELTI-PQGNLCYESTRVFLN 558
            :|.|:|    |.|            .|:.:|.  :.|:::.||.|...: ..|..|:|.:.:.|.
 Worm   480 TATVSLFLPGQTL------------VRSVKGTDVFTFENIGPGTYSARLDDNGRGCWEKSEMTLV 532

  Fly   559 VASAEEDAPPFVH---KGYEVSIISSHRALMKYTH-----VTGPSEPKAPTESLKIASGVNTFCV 615
            |  .:.:..|.:|   .|:...|..||.|.:::::     :.|.:..|        ...|.:.||
 Worm   533 V--EQSNTQPTIHFKQNGFAAQIEISHPAEIEWSNADKKQLNGKTSTK--------GGEVISICV 587

  Fly   616 KKYGSYDFKLEGCHTYDE-----SLPSKFITPEPDQLQTLIINAVAHK-TGVRVLSTEPTADSIK 674
            ...|.||..|..|:.::.     ::|...:..|         .|||.: :|...|..:..| ::.
 Worm   588 PTSGVYDVSLGSCYKFERQQFKLTVPFDGVHKE---------KAVAARISGTIDLENDKNA-AVS 642

  Fly   675 LVLESESLGQEVITPVAESHKVDGKFAYRYDTYLKPEQVLRITPVSDVLLFAPQQHEIVGSSDCV 739
            :.::|.:..:|:..|..:    :|:|.:........||:: |.|.|.:.||.|....:..:..|:
 Worm   643 IRIKSSAGDREIQVPALD----NGRFTFEEPLASSGEQLV-IVPSSKLRLFEPTSKSVTVTGKCI 702

  Fly   740 DIAFNFVATRGLILRGKVVPAIKDAKITLSFPDQPELESLEVLTSVTGEFKFGPIEESLAFDLKA 804
            :.|..|.:.||:.|.|.:.||::.|.:........:: .:|.:::..|.||.||::....:|:.|
 Worm   703 ENAVKFNSFRGIFLDGSIKPAVEKAVVKAVLKKDKDV-VIEAISNKDGAFKIGPVKRVEDYDITA 766

  Fly   805 EKESYVFSDYNRQTASFSAHKLCEISVVVKDE-AGQTLGGVLLSLSGGE----SYRKNLVTGDNG 864
            ..:.:.|:. ......|.:.||.::|:.|.|| ....|.||||||.||:    .||.|.|..:..
 Worm   767 TLDGFKFTP-TSTPGHFQSVKLSQLSIKVVDEVTNAPLDGVLLSLVGGKGAGSDYRSNNVLDETA 830

  Fly   865 AINFHSLSPSQYYLRPMMKEYKFEPNSKMIDIKDGETVSVTLVGKRFAYSIFGTVSSLNGDPFAG 929
            ..|:.:|:|.:|::|.:::||||.|::..|.:|:|:..:|.|.|||.::|.:|.:..::||....
 Worm   831 HKNYVALAPGEYFVRAILQEYKFSPSTSTIVVKEGQHENVVLKGKRVSFSAYGKMREMSGDAMKD 895

  Fly   930 VNVQATADNSCPQQPEEATSEANGQYRIRGLQPGCSYSV--RVVPDKEIVERSIPAQHTVKVANE 992
            |.::|.:: .|.....|||::.:|.||||||.|.|.|.|  :...|......|.|...||.:..|
 Worm   896 VIIEALSE-GCDLHQSEATTKEDGTYRIRGLLPDCEYQVHAKSYADGSPAPHSFPRSFTVSMTAE 959

  Fly   993 DVRDINLVAISPLKIVDITARVTATLNEHYKTLRIVMYRKGNSDSPVFSQRVGTPVNPKARLNPG 1057
            ||:.:..:|....|..||...:........:::|:|: .|.|:|    ..:|.:.|.|: .|:
 Worm   960 DVKGLEFMATITAKTTDIAVEIGMDTLPEIQSVRVVI-TKNNND----HVQVASVVAPQ-HLH-- 1016

  Fly  1058 ITVFFPRIPLDGKSYVVELQSTLSDKTYTYKLPSTTFVADRGSVFVELEFKPEVRAAEADLNQNS 1122
               :...:|.||..|.:.:::....:.:..|  :...|||:......:......||.:.|::..:
 Worm  1017 ---YLVNLPRDGVEYAIRVEAEKPPQAFAAK--TVRVVADQAMKVARVPLTSSKRANDVDISVGT 1076

  Fly  1123 ISALVLIALVAIAFFKQDLATSFL-SFV-WSKLNDVA--ADLAQRQK 1165
            ..:|.....:|:.||.|:.....| :|: |:: |..|  ||...|::
 Worm  1077 FLSLPFFVTLALVFFNQNRVLELLGTFIDWAR-NTFAPTADNHHRKR 1122

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1371	NP_610551.1	CarboxypepD_reg	120..198	CDD:290350	22/85 (26%)
		CarboxypepD_reg	319..>370	CDD:290350	17/51 (33%)
		Peptidase_M14NE-CP-C_like	841..905	CDD:304370	26/67 (39%)
		CarboxypepD_reg	914..>970	CDD:290350	21/57 (37%)
nra-4	NP_872191.1	Peptidase_M14NE-CP-C_like	307..>351	CDD:389755	16/43 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156774
Domainoid	1	1.000	188	1.000	Domainoid score	I1970
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13810
Inparanoid	1	1.050	364	1.000	Inparanoid score	I1266
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55641
OrthoDB	1	1.010	-	-		D361344at33208
OrthoFinder	1	1.000	-	-		FOG0005163
OrthoInspector	1	1.000	-	-		oto19855
orthoMCL	1	0.900	-	-		OOG6_105336
Panther	1	1.100	-	-	LDO	PTHR23303
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3347
SonicParanoid	1	1.000	-	-		X3681
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.940