Protein Alignment Cdc2rk and CTK1

DIOPT Version :10

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_012783.1
• Gene: CTK1 / 853718
• SGDID: S000001622
• Length: 528
• Species: Saccharomyces cerevisiae
• Alignment Length: 357
• Identity: 118/357 - (33%)
• Similarity: 203/357 - (56%)
• Gaps: 35/357 - (9%)

  Fly     2 SSLKSNDVD---------TNPAPDPQAPITRKGFLMSLNTGTPMPIPEQNLFGRCRPVSEFEKLN 57
            ||..|||:.         .:...:.::.|.:|         .|:.:..|.     |..|.:.::.
Yeast   137 SSNTSNDIKNGYHASKYYNHKGQEGRSVIAKK---------VPVSVLTQQ-----RSTSVYLRIM 187

  Fly    58 RVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENIVRLREVVVGK 122
            :||||:||.||:|::|.:.::|||||:|:..|::|.||:.:|||.:|:...|.|:..::|::| :
Yeast   188 QVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMV-E 251

  Fly   123 SLDSIFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMIHRDLKVSNLLMTD 187
            |..:::::.::.:.||:.:|.|.....:.|:.|.:..|:|..::|||...::|||:|.||:|:.:
Yeast   252 SQKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDN 316

  Fly   188 KGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILGELLLGKPL 252
            :|.:|:.||||||.. |.....|.:::|||||.||||||...:.|.||||..||:|.||.....:
Yeast   317 QGNLKITDFGLARKM-NSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAI 380

  Fly   253 LPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNFTLSQQP----YNNLTPKFHMIGQSGRNL 313
            ..|::|:.|::.|..::|.|:.:.||...|:|..  |.:..|.    .||.:.||..:..|.:.|
Yeast   381 FQGSNELEQIESIFKIMGTPTINSWPTLYDMPWF--FMIMPQQTTKYVNNFSEKFKSVLPSSKCL 443

  Fly   314 ---LNILFIYNPKTRATAEECLKSKYFVDPPQ 342
               :|:| .|:...|.:|.|.|:|.||.:.|:
Yeast   444 QLAINLL-CYDQTKRFSATEALQSDYFKEEPK 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	109/305 (36%)
CTK1	NP_012783.1	STKc_CDK9_like	183..469	CDD:270832	104/290 (36%)