Protein Alignment Cdc2rk and cdk7

DIOPT Version :10

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_998126.2
• Gene: cdk7 / 405897
• ZFINID: ZDB-GENE-010320-2
• Length: 345
• Species: Danio rerio
• Alignment Length: 345
• Identity: 138/345 - (40%)
• Similarity: 200/345 - (57%)
• Gaps: 37/345 - (10%)

  Fly    53 FEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRM---DQEKDGLPISGLREIMILKQCHHENIVR 114
            :|||:.:|||.:..||:|||..:|.|||:||:::   .:.|||:..:.||||.:|::..|.||:.
Zfish    12 YEKLDFLGEGQFATVYKARDKTTNTIVAIKKIKVGHRTEAKDGINRTALREIKLLQELSHPNIIG 76

  Fly   115 LREVVVGKSLDSIFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMIHRDLK 179
            |.:....||  :|.||.|:.|.||..::.:.|...|.:.:|...|..|:.|:|:|:.:::|||||
Zfish    77 LLDAFGHKS--NISLVFDYMETDLEVIIKDTSLVLTPANIKAYILMTLQGLEYMHNHWILHRDLK 139

  Fly   180 VSNLLMTDKGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILG 244
            .:|||:.:.|.:|:||||||:.|.:|.:..|.|:||.||||||||.|.|.:...|||||.||||.
Zfish   140 PNNLLLDENGVLKLADFGLAKAFGSPNRVYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILA 204

  Fly   245 ELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNFTLSQQPYNNLTPKFHMIGQS 309
            ||||..|.|.|:|::.||..|.:.||.|::.||||.:.||...:|    :|:.. ||..|:...:
Zfish   205 ELLLRVPFLAGDSDLDQLTKIFEALGTPTDEIWPGMSSLPDYVSF----KPFPG-TPLEHIFSAA 264

  Fly   310 GRNLLNI---LFIYNPKTRATAEECLKSKYFVDPPQACDPGMMPTFPQHRNNAAPAPAVQPPADI 371
            |.:||.:   ||.|||.:|.||.:.||.|||                  .|...|.|..|.|...
Zfish   265 GDDLLELLRGLFTYNPCSRTTAMQALKMKYF------------------SNRPGPTPGPQLPRPN 311

  Fly   372 PISDLLN------VFIKRQR 385
            ..::.|.      :.|||:|
Zfish   312 SSTEALKEKENLLIGIKRKR 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	128/305 (42%)
cdk7	NP_998126.2	STKc_CDK7	11..308	CDD:270833	132/320 (41%)