Protein Alignment Cdc2rk and Cdk8

DIOPT Version :10

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Alignment Length: 319
• Identity: 107/319 - (33%)
• Similarity: 176/319 - (55%)
• Gaps: 38/319 - (11%)

  Fly    58 RVGEGSYGIVYRA--RDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENIVRLREVVV 120
            :||.|:||.||:|  ::|...:..|||::    :..||.:|..|||.:|::..|:|::.|..|.:
  Fly    26 KVGRGTYGHVYKAKWKETSDGKEYALKQI----DGTGLSMSACREIALLRELKHQNVITLIRVFL 86

  Fly   121 GKSLDSIFLVMDFCEQDLASVLD-NMSQPFTESE-------VKCITLQVLKALKYLHSRFMIHRD 177
            ..:...:||::|:.|.||..::. :.:...|:.:       ||.:..|:|..:.||||.:::|||
  Fly    87 SHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSNWVLHRD 151

  Fly   178 LKVSNLLM----TDKGCIKVADFGLARMFSNPPKPMT---PQMVTLWYRAPELLLGCRTHTTAVD 235
            ||.:|:|:    .::|.:|:||.|.||:|:.|.||:.   |.:||.||||||||||.|.:|.|:|
  Fly   152 LKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAID 216

  Fly   236 MWAFGCILGELLLGKPLLPGNSEIA---------QLDMIIDLLGAPSESIWPGFADLPAVQNFT- 290
            :||.|||..|||..:|:.....|..         |||.|.:::|.|.:..|.....:|.....|
  Fly   217 IWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHHTLTK 281

  Fly   291 -LSQQPYNNLT-PKF---HMIGQSGR--NLLNILFIYNPKTRATAEECLKSKYFVDPPQ 342
             ..:..|:..: .|:   |.|....:  :||..|.:.:|..|.|:|:.::.:||.:.||
  Fly   282 DFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQEEPQ 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	107/319 (34%)
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	103/312 (33%)