Protein Alignment Cdc2rk and Cdk11b

DIOPT Version :10

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_665709.2
• Gene: Cdk11b / 252879
• RGDID: 628604
• Length: 784
• Species: Rattus norvegicus
• Alignment Length: 365
• Identity: 173/365 - (47%)
• Similarity: 240/365 - (65%)
• Gaps: 20/365 - (5%)

  Fly     9 VDTNPAPDPQAPITRKGFLMSLNTGTPMPIPEQNLFGRCRPVSEFEKLNRVGEGSYGIVYRARDT 73
            |..:||..|          :.|....|..:|.  |.| ||.|.||:.|||:.||:||:||||:|.
  Rat   396 VPDSPALSP----------IELKQELPKYLPA--LQG-CRSVEEFQCLNRIEEGTYGVVYRAKDK 447

  Fly    74 RSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENIVRLREVVVGKSLDSIFLVMDFCEQDL 138
            :::||||||:::|::||:|.||:.||||..:.:..|.|||.:||:|||.::|.|::||::.|.||
  Rat   448 KTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 512

  Fly   139 ASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMIHRDLKVSNLLMTDKGCIKVADFGLARMFS 203
            .|:::.|.|||...|||.:.:|:|..:|:||..:::|||||.||||::..|.:||.||||||.:.
  Rat   513 KSLMETMKQPFLPGEVKTLMIQLLSGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG 577

  Fly   204 NPPKPMTPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDL 268
            :|.|..||.:|||||||||||||.:.::||||||:.|||.||||..|||.||.|||.|::.:...
  Rat   578 SPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKD 642

  Fly   269 LGAPSESIWPGFADLPAVQNFTLSQQPYNNLTPKF-HMIGQSGRNLLNILFIYNPKTRATAEECL 332
            ||.|||.||||:.|||||:..|.|:.|||||..:| .::...|.:|:|....|.|..|.:||:.|
  Rat   643 LGTPSEKIWPGYNDLPAVKKMTFSEYPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRVSAEDGL 707

  Fly   333 KSKYFVDPPQACDPGMMPTFP----QHRNNAAPAPAVQPP 368
            |.:||.:.|...|..|.||:|    |.|.....:|  :||
  Rat   708 KHEYFRETPLPIDSSMFPTWPAKSEQQRVKRGTSP--RPP 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	159/308 (52%)
Cdk11b	NP_665709.2	STKc_CDC2L1	421..712	CDD:173741	151/290 (52%)