Protein Alignment Cdc2rk and MAPK15

DIOPT Version :10

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: XP_011515227.1
• Gene: MAPK15 / 225689
• HGNCID: 24667
• Length: 565
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 110/351 - (31%)
• Similarity: 178/351 - (50%)
• Gaps: 73/351 - (20%)

  Fly    63 SYGIVYRARDTRSNEIVALKKV------RMDQEKDGLPIS-------------GLREIMILKQC- 107
            :||||::|.|.|:.|:||:||:      :.|.:..|..::             ..|||.:|::.
Human    25 AYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQDMGFLLAPPTHTPVFLSLQRTFREITLLQEFG 89

  Fly   108 HHENIVRLREVVVGKSLDSIFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKYLHSRF 172
            .|.||:.|.:|:..::...|:||.:|.:.||.:|: .......:..|:.|..|:|:|.::|||..
Human    90 DHPNIISLLDVIRAENDRDIYLVFEFMDTDLNAVI-RKGGLLQDVHVRSIFYQLLRATRFLHSGH 153

  Fly   173 MIHRDLKVSNLLMTDKGC-IKVADFGLARMFSNPP-----KPMTPQMVTLWYRAPELLLGCRTHT 231
            ::|||.|.||:|: |..| :|:.||||||...:.|     :.:|..:.|.||||||:||....:|
Human   154 VVHRDQKPSNVLL-DANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHRYT 217

  Fly   232 TAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNFTLSQQPY 296
            ..||||:.||||||:|.|:||.||.|.:.||::|::.:..|||.      ||.|:.:...:.
Human   218 LGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEE------DLLALGSGCRAS--- 273

  Fly   297 NNLTPKFHMIGQSGR----------------NLLNILFIYNPKTRATAEECLKSKY---FVDP-- 340
                 ..|.:|...|                :||..|.::.|..|.:|.:.|:..|   |..|
Human   274 -----VLHQLGSRPRQTLDALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQHPYVQRFHCPSD 333

  Fly   341 ---------PQACDPGMMPTFPQHRN 357
                     |:|.: |:..:.|::|:
Human   334 EWAREADVRPRAHE-GVQLSVPEYRS 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	108/345 (31%)
MAPK15	XP_011515227.1	STKc_MAPK15-like	25..364	CDD:270841	110/351 (31%)