Protein Alignment Cdc2rk and dyf-18

DIOPT Version :10

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_502232.2
• Gene: dyf-18 / 186662
• WormBaseID: WBGene00010349
• Length: 323
• Species: Caenorhabditis elegans
• Alignment Length: 340
• Identity: 106/340 - (31%)
• Similarity: 170/340 - (50%)
• Gaps: 29/340 - (8%)

  Fly    50 VSEFEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENIVR 114
            :..:|.:...|.|::|:|..||||.:::.||:|::.:....   .:|..|||..|:..||.||::
 Worm     5 IYRYETIQVAGRGAFGLVVIARDTLTSKRVAIKRIMVPNVS---KVSLAREISCLRNLHHRNILK 66

  Fly   115 LREVVVGKSLDSIFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMIHRDLK 179
            |.:..  .|.|.:.:|.:.....|..::.:.::|.||...:....|:|..:.||||:.::|||:|
 Worm    67 LLDCF--PSADLMSIVTEEVPYTLGDIIKDKTRPKTEQFNRWYYTQILSGIAYLHSKEIMHRDIK 129

  Fly   180 VSNLLMTDKGCIKVADFGLARMF--SNPPKPMTPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCI 242
            ..|:|:|.:..:|:||||.|..:  .:|.:.....:.|.||||||||.|.:.:...||:||.|||
 Worm   130 PENILVTSRNVVKIADFGQACFYMPKDPNQEYDVNVATRWYRAPELLFGSKKYKPDVDIWAIGCI 194

  Fly   243 LGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNFTLS-QQPYNNLTPKFHMI 306
            |.||:.|||:.||.||:.|:.:|..:||.|:|..||.:..:|........ ::|.||.| :..:.
 Worm   195 LAELVRGKPIFPGRSELEQISIIFGVLGTPNEDNWPNWRTMPDANKLLFEPKEPRNNWT-EILLC 258

  Fly   307 GQSGRNLLNIL-----FIYNPKTRATAEECLKSKYFVDPPQACDPGMMPTFPQHRNNAAPAPAVQ 366
            .:...|....|     |.    .|..|.|.||..:........:|....:....|.|...|   .
 Worm   259 KEISNNFTEFLGSHLQFF----KRLKASELLKEPWIKQGLPLVEPNYRISKKSTRRNQRDA---L 316

  Fly   367 PPADIPISDLLNVFI 381
            ||        |:||:
 Worm   317 PP--------LHVFL 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	98/310 (32%)
dyf-18	NP_502232.2	Protein Kinases, catalytic domain	7..289	CDD:473864	97/291 (33%)