Protein Alignment Cdc2rk and cdk-5

DIOPT Version :10

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_499783.1
• Gene: cdk-5 / 176774
• WormBaseID: WBGene00000407
• Length: 292
• Species: Caenorhabditis elegans
• Alignment Length: 298
• Identity: 118/298 - (39%)
• Similarity: 176/298 - (59%)
• Gaps: 24/298 - (8%)

  Fly    53 FEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENIVRLRE 117
            ::|:.::|||:||.|::||:..|.||||||:||:|.:.:|:|.|.||||.||::..|.|:|||.:
 Worm     4 YDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNVVRLYD 68

  Fly   118 VVVGKSLDSIFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMIHRDLKVSN 182
            ||  .|.:.:.||.::|:|||....|:::........:.:.||:|:.|.:.|:..::|||||..|
 Worm    69 VV--HSENKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHHVLHRDLKPQN 131

  Fly   183 LLMTDKGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILGELL 247
            ||:...|.:|:|||||||.|..|.:..:.::||||||.|::|.|.:.:.|::|||:.|||..|:.
 Worm   132 LLINTNGTLKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFAEIS 196

  Fly   248 -LGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNFTLSQQPYNNLTPKFH------- 304
             .|:||.||.....||..|...||:|||..||....||       ..:||    |.:|
 Worm   197 NAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLP-------DYKPY----PIYHPTLTWSQ 250

  Fly   305 ---MIGQSGRNLLNILFIYNPKTRATAEECLKSKYFVD 339
               .:...||:||..|.:.||..|..|:..|:..||.|
 Worm   251 IVPNLNSRGRDLLQKLLVCNPAGRIDADAALRHAYFAD 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	118/298 (40%)
cdk-5	NP_499783.1	STKc_CDK5	3..286	CDD:143344	115/294 (39%)