Protein Alignment Cdc2rk and cdk-8

DIOPT Version :10

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_492357.2
• Gene: cdk-8 / 172677
• WormBaseID: WBGene00000409
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 369
• Identity: 121/369 - (32%)
• Similarity: 182/369 - (49%)
• Gaps: 64/369 - (17%)

  Fly    53 FEKLNRVGEGSYGIVYRARDTRS-----NEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENI 112
            ||....:|.|:||:||:|...:.     |:..|||.:    |..|..:|..|||.:.::..|.|:
 Worm    26 FENSKEIGRGTYGLVYKAVPKKQNGQFPNKEYALKMI----EGQGFSMSACREIALFRELRHPNL 86

  Fly   113 VRLREVVVGKSLDSIFLVMDFCEQDLASVLDNMSQPFTE--------SEVKCITLQVLKALKYLH 169
            :.|:.|.:... ..::|::|:.|.||..|:.:.....::        :.||.|..|:|..:.|||
 Worm    87 ICLQRVFLTNE-KKVWLLLDYAEHDLWHVIKHHRTAKSKKVPIMVPRNMVKNILFQILSGMHYLH 150

  Fly   170 SRFMIHRDLKVSN-LLMTD-----KGCIKVADFGLARMFSNPPKPMT---PQMVTLWYRAPELLL 225
            |.:::|||||.:| |||.|     :|.:|:||.|.:|:::||.|||.   |.:||.|||||||||
 Worm   151 SNWVLHRDLKPANILLMGDGPPDMRGRVKIADLGFSRIYANPLKPMAELDPVVVTFWYRAPELLL 215

  Fly   226 GCRTHTTAVDMWAFGCILGELLLGKPLLPGNSE---------IAQLDMIIDLLGAPSESIWPGFA 281
            |.:.:|.|:|:||.|||..|||..:||.....|         ..|:..|..|||.||::.||...
 Worm   216 GAKHYTKAIDVWAIGCIFAELLTAEPLFFCKEEDIKAQNPYHYDQVKRIFHLLGYPSDADWPDMK 280

  Fly   282 DLPAVQNFTLSQQPYNNLTP-------------KFHMIGQSG--RNLLNILFIYNPKTRATAEEC 331
            .:|..|.  |.....|..||             |:.:..||.  |.|:.:|.: :|..|.:.||.
 Worm   281 KMPDHQR--LLSDARNEGTPIQTFPNSLHRYFDKWKINSQSSPYRLLVKLLTV-DPTKRVSCEEA 342

  Fly   332 LKSKYF---VDPPQACDPGMMPTFP------QHRNNAAPAPAVQ 366
            :...||   ..||:..| .:...:|      :.:...||..|.|
 Worm   343 MNDIYFRKMERPPRETD-DVFNKYPIPYAKKEQQMTVAPDQAQQ 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	116/348 (33%)
cdk-8	NP_492357.2	STKc_CDK8_like	26..348	CDD:270834	111/329 (34%)
		Med15	<423..>566	CDD:312941