Protein Alignment Cdc2rk and cdk12

DIOPT Version :9

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: XP_012826946.1
• Gene: cdk12 / 100038049
• XenbaseID: XB-GENE-493308
• Length: 1466
• Species: Xenopus tropicalis
• Alignment Length: 425
• Identity: 143/425 - (33%)
• Similarity: 225/425 - (52%)
• Gaps: 62/425 - (14%)

  Fly    10 DTNPAPD---------PQAPITRKGFLMSLNTGTPMPIPEQNLFGRCRPVSEFEKLNRVGEGSYG 65
            |.:| ||         ||.|:.::..:.....|.... .|.:...||  |.:|:.:..:|||:||
 Frog   662 DPSP-PDSPERKVVAPPQPPLKKRPKICCPRYGERKQ-TETDWGKRC--VDKFDIIGIIGEGTYG 722

  Fly    66 IVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENIVRLREVVVGK--SLD--- 125
            .||:|:|..:.|:|||||||:|.||:|.||:.:|||.||:|..|:::|.::|:|..|  :||
 Frog   723 QVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHKSVVNMKEIVTDKQDALDFKK 787

  Fly   126 ---SIFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMIHRDLKVSNLLMTD 187
               :.:||.::.:.||..:|::....|:|..:|....|:::.|:|.|.:..:|||:|.||:|:.:
 Frog   788 DKGAFYLVFEYMDHDLMGLLESGLVQFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNN 852

  Fly   188 KGCIKVADFGLARMFSN-PPKPMTPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILGELLLGKP 251
            .|.||:|||||||::|: ..:|.|.:::|||||.||||||...:|.|:|:|:.|||||||...||
 Frog   853 SGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKP 917

  Fly   252 LLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNFTLSQQPYNNLTPKFHMIGQSGRNLLNI 316
            :...|.|:|||::|..|.|:|..::||....||........:|....|..:|..:.....:||:.
 Frog   918 IFQANQELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFVPTPALDLLDH 982

  Fly   317 LFIYNPKTRATAEECLKSKYFVDPP------------QAC------------DPGMM----PTFP 353
            :...:|..|.|||:.|:|.:..|..            |.|            ..|::    |...
 Frog   983 MLTLDPSKRCTAEQTLQSDFLKDVDVCKMATPDLPHWQDCHELWSKKRRRQRQSGIVLEEPPAIK 1047

  Fly   354 QHR------------NNAAPAPAVQPPADIPISDL 376
            ..|            .|::|||......:..:|||
 Frog  1048 APRKESVSVPGGDAMKNSSPAPTQPVKTESSVSDL 1082

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	126/344 (37%)
		S_TKc	53..337	CDD:214567	118/292 (40%)
cdk12	XP_012826946.1	STKc_CDK12	702..1003	CDD:270847	121/302 (40%)
		S_TKc	710..1003	CDD:214567	118/292 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925637at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920