Protein Alignment Cdc2rk and cdk16

DIOPT Version :10

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: XP_031762670.1
• Gene: cdk16 / 100037876
• XenbaseID: XB-GENE-5856779
• Length: 522
• Species: Xenopus tropicalis
• Alignment Length: 357
• Identity: 124/357 - (34%)
• Similarity: 195/357 - (54%)
• Gaps: 42/357 - (11%)

  Fly     4 LKSNDVDTN---PAPDPQAPITRKGFLMSLNTGTPMPIPEQNLFGRCRPVSEFE----------K 55
            :.:.|::..   || |.:.|   :|:|..|...:| |. ::.|..|.|.||..|          |
 Frog   136 ISTEDINKRLSLPA-DIRLP---EGYLEKLALSSP-PF-DKPLSRRLRRVSLSEIGFGKLETYIK 194

  Fly    56 LNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENIVRLREVVV 120
            |:::|||:|..||:.|...:..:||||::|::.| :|.|.:.:||:.:||...|.|||.|.:::
 Frog   195 LDKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANIVTLHDII- 257

  Fly   121 GKSLDSIFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMIHRDLKVSNLLM 185
             .:..::.||.::.::||...||:.........||....|:|:.|.|.|.|.::|||||..|||:
 Frog   258 -HTERTLTLVFEYLDKDLKQYLDDCGNLINLHNVKLFLYQLLRGLSYCHRRKVLHRDLKPQNLLI 321

  Fly   186 TDKGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILGELLLGK 250
            .:||.:|:|||||||..|.|.|..:.::||||||.|::|||...::|.:|||..|||..|::.|:
 Frog   322 NEKGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTEYSTQIDMWGVGCIFYEMVTGR 386

  Fly   251 PLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNFTLSQQPYNNLT-PKFH---------M 305
            ||.||::...||..|..:||.|:|..|||.          ||.:.:.:.. |:::         .
 Frog   387 PLFPGSTVEEQLHFIFRILGTPTEETWPGI----------LSNEEFKSYNYPRYYPDPIQKHAAR 441

  Fly   306 IGQSGRNLLNILFIYNPKTRATAEECLKSKYF 337
            :...|.|||..|.....:.|.:|||.::..||
 Frog   442 LDSDGANLLTKLLQLEGRNRISAEEAMRHLYF 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	113/313 (36%)
cdk16	XP_031762670.1	Protein Kinases, catalytic domain	189..485	CDD:473864	108/298 (36%)