DRSC/TRiP Functional Genomics Resources

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Protein Alignment magu and smoc1

DIOPT Version :10

Sequence 1:NP_610548.2 Gene:magu / 36048 FlyBaseID:FBgn0262169 Length:613 Species:Drosophila melanogaster
Sequence 2:XP_021322766.1 Gene:smoc1 / 100529120 ZFINID:ZDB-GENE-110310-7 Length:516 Species:Danio rerio


Alignment Length:692 Identity:151/692 - (21%)
Similarity:231/692 - (33%) Gaps:266/692 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 LARCVLFVTWLAVFIATGKSDDQLMKLPACAAKQG----------------ECDDNEG-PVCGTD 49
            ||.||..  :|.|           |:|||.:.::.                .|..:.| ||||:|
Zfish     6 LALCVFM--YLMV-----------MRLPAASTQKSTGPRWLIGDRESPCSTSCSRSHGKPVCGSD 57

  Fly    50 GQTYPTRCHLLRAQCGGHQVSLKYSGSCNA--------------------------------C-- 80
            |::|.|.|.|.||:|....::|.:.|.|..                                |  
Zfish    58 GRSYDTNCDLERAKCRDRTLTLAHRGRCKGKNWVRIDQPLLVPTLVSEVKELTGMKEAGQTKCRT 122

  Fly    81 --LEAVKFARRQQERDPGYFVPRCRKDGNFAAMQCYGNNG-CWCSDSQGRPIADDNKQFRRKGKL 142
              ::|::.|::.||   ..|:|.|..||.||.:||:...| |||..:.|:|::            
Zfish   123 ERIQALEQAKKPQE---SIFIPECNDDGTFAQVQCHTLTGYCWCVTTDGKPVS------------ 172

  Fly   143 RCRANRRDRRRLASHQIGYNPDTSASKGSSEAGSTAHRTCSKSDRSQFNTNLMRMFRNEAQSFFR 207
                                       |||....|.  .||                        
Zfish   173 ---------------------------GSSVQNKTP--VCS------------------------ 184

  Fly   208 QPSLSDSHILEWQFSKLDTNGNKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYCDVTKDANLNWL 272
                                ||                                           
Zfish   185 --------------------GN------------------------------------------- 186

  Fly   273 EWSVCFTKEFHNRSAVVNLLASSAATAPP------HSTHYSIHNTNVNGHHRGHTNTIGTGVNPH 331
                  .:||....|..:.|:.|....||      ....:....|                :||.
Zfish   187 ------FREFMGTHAGTSGLSGSVTDKPPGPPSSGKKVSFRFFLT----------------LNPD 229

  Fly   332 SYSEDASGSEEHEDNYEDSATGYGGEEDDSQGADLPSSRTHIPSL-YMLNSKPETASQDLENDSN 395
            ..|:.....|.|.               ..:|.::.:....|..| |..|.:..:.|:..|...:
Zfish   230 DGSKPTPTMEPHV---------------VPEGEEITAPTLWIKQLVYKENKQNSSNSRKSEKVPS 279

  Fly   396 CWMDQSVTLEEQGHGGKSVLFVPQCLPDGRYQRIQCYSSTSTSYCWCVNEDTGKSIPGTSVKNKR 460
            |..::....:|.....:..:|:|.|...|.|:.:||:.  ||.|||||..|||:.|||||.:.|:
Zfish   280 CDQERQTAQDEARQNPREAIFIPDCGLQGLYKPVQCHQ--STGYCWCVLVDTGRPIPGTSARYKK 342

  Fly   461 PQCDESVAV-----------RPMKGCTEPRKTQFLKELKAYLNTSLLP--SSTTGSNSSMW---- 508
            |:||.:...           |.:.||.|.:|.:|:..|...|.|.::.  :|.|.|....:    
Zfish   343 PECDSAARSRDTEMEDPFRDRDLTGCPEGKKVEFITSLLDALTTDMVQAINSPTPSGGGRFVEPD 407

  Fly   509 --KTDDERIATLSFVYLDKNKNKSWDRREWKNFRDLVTSASHLRRCGKKMPRYCDVNGDKKISLA 571
              .|.:||:....|..||.|.:...:::|.|.|:..|...:..:||.:|...|||:|.||.|||.
Zfish   408 PSHTLEERVVHWYFAQLDNNGSHDINKKEMKPFKRYVKKKAKPKRCARKFTDYCDLNKDKTISLQ 472

  Fly   572 EWLNCLQATPRESATTAKPAQSNETASPKFQGV-NPVERYLK 612
            |...|| ...:|.:||:. :|.....:..|..| .|.:|.|:
Zfish   473 ELKGCL-GVNKEGSTTSS-SQGTRQGTNLFSKVFGPEDRKLQ 512

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
maguNP_610548.2 KAZAL_FS 38..77 CDD:238052 17/39 (44%)
TY 88..139 CDD:238114 17/51 (33%)
EFh_SPARC_SMOC 182..280 CDD:320013 4/97 (4%)
EF-hand motif 213..245 CDD:320013 2/31 (6%)
EF-hand motif 250..280 CDD:320013 0/29 (0%)
TY 396..463 CDD:238114 26/66 (39%)
EFh_SPARC_SMOC 475..577 CDD:320013 34/109 (31%)
EF-hand motif 512..544 CDD:320013 9/31 (29%)
EF-hand motif 549..577 CDD:320013 13/27 (48%)
smoc1XP_021322766.1 KAZAL 41..85 CDD:197624 17/43 (40%)
Thyroglobulin_1 120..183 CDD:459665 24/106 (23%)
Thyroglob_assoc 201..272 CDD:435450 14/101 (14%)
Thyroglobulin_1 280..345 CDD:459665 26/66 (39%)
EFh_SPARC_SMOC1 368..482 CDD:320019 36/114 (32%)
EF-hand motif 413..445 CDD:320019 9/31 (29%)
EF-hand motif 450..482 CDD:320019 15/32 (47%)

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