Protein Alignment Etf-QO and Etfdh

DIOPT Version :8

• Sequence 1: NP_001246231.1
• Gene: Etf-QO / 36031
• FlyBaseID: FBgn0286783
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_080070.2
• Gene: Etfdh / 66841
• MGIID: 106100
• Length: 616
• Species: Mus musculus
• Alignment Length: 592
• Identity: 395/593 (67%)
• Similarity: 477/593 (80%)
• Gaps: 4/593 (1%)

  Fly    16 PALARSISDVAKYPRITTHYTLNPREKDERWTEVDMERCVEEVDLVIVGGGPAGMSAAIRAKQLA 80
            |..|...|..:..|:||||||::|||||:||..|:|||..||.|:||||.||||:|||||.||||
Mouse    26 PLCAPRCSSTSAVPQITTHYTVHPREKDKRWEGVNMERFAEEADVVIVGAGPAGLSAAIRLKQLA 90

  Fly    81 AEKDQEIRVCVVEKAAEVGGHILSGAVIDPISLNELIPDWQEQGAPLNTPVTKDTFSFLTGSGRI 145
            ||:.::||||:|||||::|.|.||||.:||.:..||.|||:|:|||||||||:|.|:.||...||
Mouse    91 AEQGKDIRVCLVEKAAQIGAHTLSGACLDPAAFKELFPDWKEKGAPLNTPVTEDRFAILTEKHRI 155

  Fly   146 SIPVFKGWPMDNHGNYVVRLGHLVKWLGDQAEALGVEIYPGCAASEVLFHEDGSVKGIATNDVGI 210
            .:|:..|.||:|||||:|||||||.|:|:||||||||:|||.||:|||:||||||||||||||||
Mouse   156 PVPILPGLPMNNHGNYIVRLGHLVSWMGEQAEALGVEVYPGYAAAEVLYHEDGSVKGIATNDVGI 220

  Fly   211 AKSGAPKDTFARGMELHAKTTIFAEGCRGHLTKQIMQKFGLNEGSEPQAYGIGLKEVWEIAPEKH 275
            .|.||||.||.||:|||||.|:|||||.|||.||:.:||.|....:.|.|||||||:|.|..:|.
Mouse   221 QKDGAPKTTFERGLELHAKVTVFAEGCHGHLAKQLYKKFDLRASCDAQTYGIGLKELWIIDEKKW 285

  Fly   276 QPGLVEHTIGWPLDRFTYGGSFLYHLNEPTPTIAVGFVVGLNYKNPWLSPFQEFQRFKTHPKVRD 340
            :||.|:||:||||||.||||||||||||..|.:||||||||:|:||:||||:||||:|.||.::.
Mouse   286 KPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLVAVGFVVGLDYQNPYLSPFREFQRWKHHPSIQP 350

  Fly   341 VFEGATRIAYGARAINEGGFQSLPQKLSFPGGCLVGCSAGFLNVPRIKGSHYAMKSGMLAAESAF 405
            ..||..||||||||:||||.||:| ||:||||.|:|||.||:|||:|||:|.|||||.|||||.|
Mouse   351 TLEGGKRIAYGARALNEGGLQSIP-KLTFPGGLLIGCSPGFMNVPKIKGTHTAMKSGSLAAESIF 414

  Fly   406 EAINAD--AQSTAGVEPTGYAEKIKDSFVWKDLYSVRNVHPSFHNPLGLYGGLVLSG-FSIFMGG 467
            :.:.::  ...|.|:..|.|.:.:|.|:|||:|::|||:.||.|..||:|||::.:| |...:.|
Mouse   415 KQLTSENLQSKTTGLHVTEYEDNLKQSWVWKELHAVRNIRPSCHGILGVYGGMIYTGIFYWILRG 479

  Fly   468 REPWTLKHGPQDHESLKPASSCPPIVYPKPDGKISFDLLSSVALTGTNHEGDQPAHLTLKDDRIP 532
            .|||||||...|.:.||||..|.||.||||||:|||||||||||:|||||.|||||||||||.||
Mouse   480 MEPWTLKHKGSDSDQLKPAKDCTPIEYPKPDGQISFDLLSSVALSGTNHEHDQPAHLTLKDDSIP 544

  Fly   533 VDHNLALYEGPEQRFCPAGVYEYVPNEEGGNMKLQINAQNCIHCKTCDIKDPKQNINWVVPEGGG 597
            |:.||::|:|||||||||||||:||.|:|...:||||||||:||||||||||.||||||||||||
Mouse   545 VNRNLSIYDGPEQRFCPAGVYEFVPLEQGDGFRLQINAQNCVHCKTCDIKDPSQNINWVVPEGGG 609

  Fly   598 GPAYNGM 604
            |||||||
Mouse   610 GPAYNGM 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Etf-QO	NP_001246231.1	NADB_Rossmann	44..>206	CDD:304358	111/162 (69%)
		FixC	56..516	CDD:223717	301/463 (65%)
		ETF_QO	499..602	CDD:282972	85/103 (83%)
Etfdh	NP_080070.2	FixC	66..528	CDD:223717	301/463 (65%)
		NADB_Rossmann	67..>261	CDD:304358	136/194 (70%)
		ETF_QO	511..614	CDD:282972	85/103 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C326650751
eggNOG	1	0.900				E1_COG2440
Hieranoid	1	1.000
Homologene	1	1.000				H3275
Inparanoid	1	1.050	846	1.000	Inparanoid score	I430
Isobase	1	0.950		0	Normalized mean entropy	S422
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0004291
OrthoInspector	1	1.000				T1083029
orthoMCL	1	0.900				OOG5_128337
Panther	1	1.100			LDO	PTHR10617
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R420
TreeFam	1	0.960
	14	13.740