Protein Alignment CG1513 and osbp2b

DIOPT Version :10

• Sequence 1: NP_610534.3
• Gene: CG1513 / 36028
• FlyBaseID: FBgn0033463
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_021331891.1
• Gene: osbp2b / 561797
• ZFINID: ZDB-GENE-060526-3
• Length: 822
• Species: Danio rerio
• Alignment Length: 870
• Identity: 179/870 - (20%)
• Similarity: 322/870 - (37%)
• Gaps: 243/870 - (27%)

  Fly     4 TTGSAPSLGPPQSGSGGSGTLEGTLSKWTNVMKGWQYRFFVLDENAGLLSYYTSKDKMIKGVRRG 68
            :..|.|:.|.|   :.||.|.:|.|.||||.:||:|.|:|||..  ||||||.::.:|.. ..||
Zfish    56 SAASTPASGTP---APGSDTYKGWLFKWTNYIKGYQRRWFVLSN--GLLSYYRTQAEMAH-TCRG 114

  Fly    69 CVRLKDALIGIDDQEDNTFTITVDHKTFHFQARHNEEREQWVRRLE----DTIRRHANRSRLWDS 129
            .:.|  |...||.::.....::...:|:|.:|....||::||..||    ..||...::|   |:
Zfish   115 TINL--ATAHIDTEDACNIVLSSGGRTYHLKASTEVERQRWVTALELAKAKAIRMMNDQS---DN 174

  Fly   130 QSAFYIAGGYTKEGGGSGTGGRRPNHLEL------VARRVSEADAYLQLMIEQTNLLDKRIAELT 188
            .....:...|..:.........:.:|.|:      :|.::.:.....:|:.:....|.:.::||.
Zfish   175 GHTASLTHCYQSDDSADEEPTSQSDHSEIQGTLKTLASKLDDLSTCNELIAKHGAALQRSLSELE 239

  Fly   189 D---PAE-QSKCKALQDNA-------NAMLD----------------------------HIKHSI 214
            .   |.| ..|.||:.:.|       |||::                            |::.:|
Zfish   240 TLRVPLEGGEKIKAVNERATLFRITSNAMINACRDFLELAESHSRRWQRVLQHEREQRTHLEETI 304

  Fly   215 VSLQIAKNM---------AHPINGIYNGPPATASTSSSTSGVAMGSCNNVQAGGLKVPLEGQVIG 270
            ..|....|.         ||.:|        |..|.::.:||:                  :...
Zfish   305 EQLAKQHNSLERAWREAPAHAVN--------TPDTPTTDTGVS------------------ERPR 343

  Fly   271 KGELVDDEEDSATENATTAPLGLIVPATSYSSSEGEEDFYDAYDDPFTSIGSSPIGCATRGFAET 335
            |.|..|::||:                          :::||.:|       ||....    ...
Zfish   344 KEEASDEDEDT--------------------------EYFDAMED-------SPAFIT----VTA 371

  Fly   336 TSPT-HEKAPDGFANAEPVAVGDSVAPQTLPEIDE-SVADADTSIKTARTAVSSRSASYDNGIDY 398
            |.|: |.::....:.|      ....|....:.|. ||:..|.|.|..:.....||
Zfish   372 TDPSQHRRSQSNLSGA------SGGQPSDWNQDDNCSVSSNDFSGKELQPRRKRRS--------- 421

  Fly   399 DALYEEEEETDLSMEAHGSMITHLLSQVK--IGMDLTKVVLPTFILERRSLLEMYADYFAHPDLF 461
                ...|:.:.|:        :|.|.:|  ||.:|:|:.:|....|..|:|:...:...:.:|.
Zfish   422 ----RISEKPNYSL--------NLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELL 474

  Fly   462 IKISDLDDPRDRIVQVCRWYMSAYHAG-RKSAVAKKPYNPILGEVFQCHWDIPGISQDAQEVRDG 525
            .|.:..::..:::..|..:.:|:|... .::|   ||:||:|||.::..
Zfish   475 DKAARCENSLEQMCLVAAFSVSSYSTTVHRTA---KPFNPLLGETYELD---------------- 520

  Fly   526 PVPWCRRDQLTF--LAEQVSHHPPISAFYAEHYN-----KKITFAAHVWTKSKFLGLSIGVHNIG 583
                 |.::..:  |.||||||||.:|.:.....     ::||.|      |||.|..:.:..:|
Zfish   521 -----RLEEFGYRSLCEQVSHHPPAAAHHVVSQRGWSLWQEITIA------SKFRGKYLSIMPLG 574

  Fly   584 EGVVTLVDRSEEYI---VTFPNGYGRSILTVPWIELGGSVEIKCPQSGYYANVEFLTKPFYGGKR 645
            ...:........|:   ||  :.....|:...||:..|.::|...::.....::|....::..:.
Zfish   575 AIHLQFHASGNHYVWRKVT--STVHNIIVGKLWIDQSGDIDIVNHRTKETCQLKFSPYSYFSREV 637

  Fly   646 NRVSAEVYAPSEKKPFVSITGEWSGLME-----------AKWHDKNKTEVFVDVNRIPIFKKQVR 699
            .|....|...|:.:....::|.|...||           :....|.|| |:..::...::||...
Zfish   638 PRKVTGVVMDSDGQANYILSGTWDEKMESAKIVQSSRGSSSSEGKQKT-VYQTLSPKLLWKKYPL 701

  Fly   700 PIVEQDEY---ESRRVWKEVTAGLKFNDI--------------ERATTAKFVVEQQQ-----RDQ 742
            |...::.|   .......|...|:...|.              :.|...|..:|::|     |.:
Zfish   702 PENAENMYYFSSLALTLNEEEDGVSITDSRLRPDQRLMEAGRWDEANAEKQRLEEKQRAVRRRRE 766

  Fly   743 AKVRKEYDLAWEHKHFKPVGDNWIY 767
            |:..:..|...:.:.:||:   |.:
Zfish   767 AEASRAIDEGEDFEGYKPL---WFH 788

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1513	NP_610534.3	PH_ORP9	24..125	CDD:241444	37/104 (36%)
		Oxysterol_BP	421..767	CDD:460126	80/391 (20%)
osbp2b	XP_021331891.1	PH_OSBP_ORP4	73..168	CDD:270101	37/99 (37%)
		Oxysterol_BP	432..811	CDD:460126	80/393 (20%)