Protein Alignment CG1513 and Osbp

DIOPT Version :10

• Sequence 1: NP_610534.3
• Gene: CG1513 / 36028
• FlyBaseID: FBgn0033463
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_477271.1
• Gene: Osbp / 42985
• FlyBaseID: FBgn0020626
• Length: 784
• Species: Drosophila melanogaster
• Alignment Length: 929
• Identity: 202/929 - (21%)
• Similarity: 333/929 - (35%)
• Gaps: 300/929 - (32%)

  Fly     1 MASTTGSA-PSLGPPQSGSGGSGTLEGTLSKWTNVMKGWQYRFFVLDENAGLLSYYTSKDKMIKG 64
            |....|:| ...|.|:        ::|.|.||||.:||:|.|:|||.:  |:||||.::.: |..
  Fly     1 MTDAAGNALAEKGLPE--------MKGWLLKWTNYIKGYQRRWFVLSK--GVLSYYRNQSE-INH 54

  Fly    65 VRRGCVRLKDALIGIDDQEDNTFTIT-VDHKTFHFQARHNEEREQWVRRL--------------- 113
            ..||.:.|..|||...|  ..||.|: ...:|||.:|....||:.||..|
  Fly    55 TCRGTISLHGALIHTVD--SCTFVISNGGTQTFHIKAGTEVERQSWVTALELAKAKAIRAIECEE 117

  Fly   114 -EDTIRRHANRS------------RLWDSQSAFYIAGGYTKEGGGSGTGGRRPNHLELVARRVSE 165
             |:|...|...|            ||...::.:.:   .||.|...   .|..|.||     .:|
  Fly   118 EEETETAHVVPSQEISSVVRDLTDRLESMRTCYDL---ITKHGAAL---QRALNDLE-----TNE 171

  Fly   166 ADAYLQLMIEQTNLLDKR--IAELTDPAEQSKCKALQDNANA-------MLDHIKHSIVSL-QIA 220
            .::    :..:|.::::|  :..:|..|..:........|.|       ||.|.:.....| :|.
  Fly   172 EES----LGSRTKIVNERATLFRITSNAMINAGNDYLHTAEAQGHKWSKMLHHEREQRQRLEEII 232

  Fly   221 KNMAHPINGIYNGPPATASTSSSTSGVAMGSCNNVQAGGLKVPLEGQVIGKGELV-DDEEDSATE 284
            :.||..                                      :.|:.....|| .::..|:|.
  Fly   233 EQMAKQ--------------------------------------QSQMEQAAVLVRQNKPVSSTS 259

  Fly   285 NATTAPLGLIVPATSYSSSEGEEDFYDAYDDPFTSIGSSP--IGCATRGFAETTSPTHEKAPDGF 347
            .|.||  |.:|      :|:.|.:|:||.:..::..|.||  ..|....|..........:.|
  Fly   260 GAGTA--GSLV------TSDEEMEFFDAEEHGYSGSGRSPESSDCERGTFILKMHKRRSSSED-- 314

  Fly   348 ANAEPVAVGDSVAPQTLPEIDESVADADTSIKTARTA-----VSS-RSASYDNGID--------- 397
                          |....::.|.:::|...:|.:|.     ||: |.||...|.|
  Fly   315 --------------QVEGHLEGSSSESDEQKRTVQTVQQVCLVSAPRVASGGQGDDDDDVDKALP 365

  Fly   398 ----YDALYEEEEETDLSMEA---------HGSMITHLLSQVKIGMDLTKVVLPTFILERRSLLE 449
                .|::|......||..:.         |...:..::... ||.||:|:.:|....|..|:|:
  Fly   366 AKESTDSIYGRNWNPDLIKKRRDRVPDKPNHPISLWGIMKNC-IGKDLSKIPMPINFNEPLSMLQ 429

  Fly   450 MYADYFAHPDLFIKISDLDDPRDRIVQVCRWYMSAYHAGRKSAVAKKPYNPILGEVFQCHWDIPG 514
            ...:.:.:.::....:...|..:::..:..:.:|||  ...:....||:||:|||.::|.
  Fly   430 RLVEDYEYTEILDYAATCQDECEQLAYIAAFTVSAY--ATTTNRTGKPFNPLLGETYECD----- 487

  Fly   515 ISQDAQEVRDGPVPW-CRRDQLTFLAEQVSHHPPISAFYAEHYNKKITFAAHVWT-------KSK 571
                    |.....| |       ||||||||||::|.:.|..|         ||       .||
  Fly   488 --------RMDDYGWRC-------LAEQVSHHPPVAALHCESKN---------WTCWQEFSMTSK 528

  Fly   572 FLGLSIGVHNIGEGVVTLVDRSEEYIVTFPNG---YG-RSILTVP--------WIELGGSVEI-- 622
            |.|..:.::.:| ||          .|.|||.   |. |.:.|..        |::..|.:||
  Fly   529 FRGKYVQINPLG-GV----------YVQFPNSGRRYSWRKVTTTVNNIIVGKLWVDQHGEMEIRG 582

  Fly   623 -------KC-----PQSGYYANVEFLTKPFYGGKRNRVSAEVYAPSEKK----PFVSITGEWS-- 669
                   ||     |.|.:..:|:...|.....|.|.|...|....:.|    |.:..:|..|
  Fly   583 SQAAEGHKCILNFIPYSYFSRDVQRSVKGVVMNKDNEVKWVVRGTWDMKIEIAPVLKTSGSVSSP 647

  Fly   670 ----GLMEAKWH--------DK--NKTEVFVDVNR----IPIFKKQVRP---IVEQDEYESRRVW 713
                |..:..|.        ||  |.|.:...:|.    :.....::||   ::||.:      |
  Fly   648 TYTTGEFKLAWRRRPAPPDSDKFYNFTTLACQLNEEEEGVAPTDSRLRPDQRLMEQGD------W 706

  Fly   714 KEVTAGLKFNDIERATTAKFVVEQQQRDQAKVRKE--------------YDLAWEHKHFKPVGDN 764
            .|            :...|..:|::||.:.:.|:.              |:..|..:..:...:.
  Fly   707 DE------------SNKEKLRLEEKQRTERRRRENEAEEAAAEGRPYPAYEPMWFKREKEEGSEE 759

  Fly   765 WIYAKPLSQRMYLQEKEAK 783
            :::   :.:..|.:.|.|:
  Fly   760 YVH---VFKNTYWEAKAAQ 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1513	NP_610534.3	PH_ORP9	24..125	CDD:241444	42/129 (33%)
		Oxysterol_BP	421..767	CDD:460126	91/420 (22%)
Osbp	NP_477271.1	PH_OSBP_ORP4	17..113	CDD:270101	38/100 (38%)
		Oxysterol_BP	399..773	CDD:460126	92/437 (21%)