Protein Alignment CG1513 and Osbpl8

DIOPT Version :10

• Sequence 1: NP_610534.3
• Gene: CG1513 / 36028
• FlyBaseID: FBgn0033463
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_780698.2
• Gene: Osbpl8 / 237542
• MGIID: 2443807
• Length: 889
• Species: Mus musculus
• Alignment Length: 768
• Identity: 209/768 - (27%)
• Similarity: 318/768 - (41%)
• Gaps: 205/768 - (26%)

  Fly    24 LEGTLSKWTNVMKGWQYRFFVLDENAGLLSYYTSKDKMIKGVRRGCVRLKDA-LIGIDDQEDNTF 87
            :.|||..||   |.|    .||.... ||.|.|.|:    |...|.|.|... :|....::|.
Mouse   157 IRGTLKSWT---KLW----CVLKPGV-LLIYKTQKN----GQWVGTVLLNACEIIERPSKKDG-- 207

  Fly    88 TITVDHKTFHFQARHNEEREQWVRRLEDTIRRHANRSRLWDSQSAFYIAGGYTKEGGGSGTGGRR 152
                    |.|:..|..|:..|..:                         |...|..||.|....
Mouse   208 --------FCFKLFHPLEQSIWAVK-------------------------GPKGEAVGSITQPLP 239

  Fly   153 PNHLELVARRVSEADAYLQLMIEQTNLLDKRIAELTDPAEQS-KCKALQDNANAMLDHIKHSIVS 216
            .::  |:.|..||:|....:                |..|.: ||.:|          :|.::|.
Mouse   240 SSY--LIIRATSESDGRCWM----------------DALELALKCSSL----------LKRTMVR 276

  Fly   217 LQIAKNMAHPINGIYNGPPATASTSSSTSGVAMGS---CNNVQAGG----LKVPLEGQVIGKGEL 274
                           .|.....|.||.::.|.:..   .||:.:|.    ....:|.|.....:|
Mouse   277 ---------------EGKEHDLSISSDSTHVTLYGLLRANNLHSGDNFQLNDSEIERQHFKDQDL 326

  Fly   275 VDDEEDSATENATTAPLGLIVPATSYSSSEGEEDFYDAYDDPFTSIGSSPIGCATRGFAETTSPT 339
            ..|:.|...:             ..:..|:.|            .:|.|         .|:.:.|
Mouse   327 YSDKSDKEND-------------PEHDESDNE------------VLGKS---------EESDTDT 357

  Fly   340 HEKAPDGFANAEPVAVGDSVAPQTLPEIDESVADADTSIKTARTAVSSRSASYDNGIDYDALYE- 403
            .|:..|.:.:.|||        :.|.|                |....:|        ::.|.|
Mouse   358 SERQDDSYIDPEPV--------EPLKE----------------TTYMEQS--------HEELGEA 390

  Fly   404 -EEEETDLSMEAHGSMITHLLSQVKIGMDLTKVVLPTFILERRSLLEMYADYFAHPDLFIKISDL 467
             |..:|:...|.:.|:|..||.||:.||||::|||||||||.||.|:..:||:.|.|...:.:..
Mouse   391 GEASQTETVSEENKSLIWTLLKQVRPGMDLSRVVLPTFILEPRSFLDKLSDYYYHADFLSEAALE 455

  Fly   468 DDPRDRIVQVCRWYMSAYHAGRKSAVAKKPYNPILGEVFQCHWDIPGISQDAQEVRDGPVPWCRR 532
            ::|..|:.:|.:||:|.::  :|....||||||||||.|:|.|..|                 |.
Mouse   456 ENPYFRLKKVVKWYLSGFY--KKPKGLKKPYNPILGETFRCLWIHP-----------------RT 501

  Fly   533 DQLTF-LAEQVSHHPPISAFYAEHYNKKITFAAHVWTKSKFLGLSIGVHNIGEGVVTLVDRSEEY 596
            :..|| :||||||||||||||..:.......:..:..||||.|.|:.....||..:|.::|.|:|
Mouse   502 NSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDY 566

  Fly   597 IVTFPNGYGRSIL--TVPWIELGGSVEIKCPQSGYYANVEFLTKPFYGGKR--NRVSAEVYAPSE 657
            ::|.|..:.:.||  |:. :||||:|.|.|.::||.|.:||..|||.|...  |::|.::  ...
Mouse   567 VMTMPYAHCKGILYGTMT-LELGGTVNITCQKTGYSAILEFKLKPFLGSSDYVNQISGKL--KLG 628

  Fly   658 KKPFVSITGEWSGLMEAKWHDK--NKTEVF----VDVNRIPIFKKQVRPIVEQDEYESRRVWKEV 716
            |:...::.|.|..  |...:||  :.:|:|    .|:.:..:.:..|: ..|||::||.::|:.|
Mouse   629 KEVLATLEGHWDS--EVFINDKKTDNSEIFWNPTPDIKQWRLIRHTVK-FEEQDDFESEKLWQRV 690

  Fly   717 TAGLKFNDIERATTAKFVVEQQQRDQAKVRKEYDLAWEHKHFK--PVGDNWIY 767
            |..:...|...||..|:|:|:.||..|:.||.....|..|.|:  |:...|.|
Mouse   691 TKAINAKDQTEATQEKYVLEEAQRQAARDRKTKTQEWVCKLFELDPLTGEWHY 743

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1513	NP_610534.3	PH_ORP9	24..125	CDD:241444	25/101 (25%)
		Oxysterol_BP	421..767	CDD:460126	131/358 (37%)
Osbpl8	NP_780698.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..129
		PH_OPR5_ORP8	142..271	CDD:270103	40/188 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	321..374		14/94 (15%)
		Oxysterol_BP	407..753	CDD:460126	133/362 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	772..823