Protein Alignment CG1513 and OSBPL9

DIOPT Version :10

• Sequence 1: NP_610534.3
• Gene: CG1513 / 36028
• FlyBaseID: FBgn0033463
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001403221.1
• Gene: OSBPL9 / 114883
• HGNCID: 16386
• Length: 754
• Species: Homo sapiens
• Alignment Length: 815
• Identity: 384/815 - (47%)
• Similarity: 517/815 - (63%)
• Gaps: 115/815 - (14%)

  Fly     4 TTGSAPSLGPPQSGSGGSGTLEGTLSKWTNVMKGWQYRFFVLDENAGLLSYYTSKDKMIKGVRRG 68
            |:|...||..|:..|    .:||.||||||||||||||:||||.||||||||||||||::|.|||
Human     7 TSGRLLSLAAPKMAS----IMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRG 67

  Fly    69 CVRLKDALIGIDDQEDNTFTITVDHKTFHFQARHNEEREQWVRRLEDTIRRHANRSRLWDSQSAF 133
            ||||:.|:|||||::|:|||||||.||||||||..:|||:|:..||:||.||..:.:..||
Human    68 CVRLRGAVIGIDDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDS---- 128

  Fly   134 YIAGGYTKEGGGSGTGGRRPNHLELVARRVSEADAYLQLMIEQTNLLDKRIAELTDPAEQSKCKA 198
                            |..|: ::...::::|||||||::|||..|.|.::....:..::.|.:.
Human   129 ----------------GFVPS-VQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIET 176

  Fly   199 LQDNANAMLDHIKHSIVSLQIAKNMA-------------HPINGIYNGPPATASTSSSTSGVAMG 250
            |::..|:|::.|||.||.|||||:.:             :|::.||...|.....|:..|...:.
Human   177 LKETTNSMVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLP 241

  Fly   251 S-----CNNVQAGGLKVPLEGQVI--------------GKGELVDDEEDSATENATTAPLGL--- 293
            .     |.:.|... .:|: |.|:              |.|.       |...::.|:|..:
Human   242 PEPVQLCKSEQRPS-SLPV-GPVLATLGHHQTPTPNSTGSGH-------SPPSSSLTSPSHVNLS 297

  Fly   294 --IVPATSYSSSEGEEDFYDAYDDPFTSIGSSPIGCATRGFAETTSPTHEKAPDGFANAEPVAVG 356
              .||..|||||  |::||||  |.|...||||                ::..|...:|..:...
Human   298 PNTVPEFSYSSS--EDEFYDA--DEFHQSGSSP----------------KRLIDSSGSASVLTHS 342

  Fly   357 DSVAPQTLPEIDESVADADTSIKTARTAVSSRSASYDNGIDYDALYEEEEETD-----LSMEAHG 416
            .|......|:..||:                 ::|..||.....|::..::.|     .|:|.|.
Human   343 SSGNSLKRPDTTESL-----------------NSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHK 390

  Fly   417 SMITHLLSQVKIGMDLTKVVLPTFILERRSLLEMYADYFAHPDLFIKISDLDDPRDRIVQVCRWY 481
            |:|.||||||::|||||||||||||||||||||||||:|||||||:.|||..||:||:|||.:||
Human   391 SVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWY 455

  Fly   482 MSAYHAGRKSAVAKKPYNPILGEVFQCHWDIPGISQDAQE-VRDGPVPWCRRDQLTFLAEQVSHH 545
            :||:|||||.:||||||||||||:|||||.:|..:::..| |.:|||||..::.:||:|||||||
Human   456 LSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHH 520

  Fly   546 PPISAFYAEHYNKKITFAAHVWTKSKFLGLSIGVHNIGEGVVTLVDRSEEYIVTFPNGYGRSILT 610
            |||||||||.:||||.|.||:||||||||:||||||||:|.|:.:|..|.||:||||||||||||
Human   521 PPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT 585

  Fly   611 VPWIELGGSVEIKCPQSGYYANVEFLTKPFYGGKRNRVSAEVYAPSEKKPFVSITGEWSGLMEAK 675
            |||:||||...|.|.::||.||:.|.||||||||::|::||:::|::||.|.||.|||:|:|.||
Human   586 VPWVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAK 650

  Fly   676 WHDKNKTEVFVDVNRIPIFKKQVRPIVEQDEYESRRVWKEVTAGLKFNDIERATTAKFVVEQQQR 740
            :.....| ||||..::||.||:||.:.:|:|||||.:||:||..||..||:.||.||..:|::||
Human   651 YATGENT-VFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQR 714

  Fly   741 DQAKVRKEYDLAWEHKHFKPVGDNWIYAKPLSQRM 775
            .:|:.|||.::.||.:.|...|:.|:|.:||.:|:
Human   715 AEARERKEKEIQWETRLFHEDGECWVYDEPLLKRL 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1513	NP_610534.3	PH_ORP9	24..125	CDD:241444	74/100 (74%)
		Oxysterol_BP	421..767	CDD:460126	220/346 (64%)
OSBPL9	NP_001403221.1	PH_ORP9	23..124	CDD:241444	74/100 (74%)
		Oxysterol_BP	395..741	CDD:460126	220/346 (64%)