DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1513 and OSBPL5

DIOPT Version :10

Sequence 1:NP_610534.3 Gene:CG1513 / 36028 FlyBaseID:FBgn0033463 Length:784 Species:Drosophila melanogaster
Sequence 2:NP_065947.1 Gene:OSBPL5 / 114879 HGNCID:16392 Length:879 Species:Homo sapiens


Alignment Length:553 Identity:165/553 - (29%)
Similarity:257/553 - (46%) Gaps:86/553 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   263 PLEGQVIG----KGELVDDEEDSATENATTAPLGLIVPATSY------SSSEGEEDFYDAYD--- 314
            ||:..|..    |||.|         .:.|.||     .:||      |.|:| ..:.||.:   
Human   193 PLDQSVWAVKGPKGESV---------GSITQPL-----PSSYLIFRAASESDG-RCWLDALELAL 242

  Fly   315 -----------------DPFTSIGSSPIGCATRGFAETTSPTHEKAPDGFANAEPVAVGDSVAPQ 362
                             :|.||..:||........:.|..|..:..|...::.|..|..|....:
Human   243 RCSSLLRLGTCKPGRDGEPGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERE 307

  Fly   363 TLPEIDESVADADTSIKTARTAVSSRSASYDNGIDYDALYEEE-------EETDLSMEAHGSMIT 420
            ...|.|....|.....::......:..|....|..|....:||       .:.:...|.:.|::.
Human   308 NPEESDTETQDHSRKTESGSDQSETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENKSLMW 372

  Fly   421 HLLSQVKIGMDLTKVVLPTFILERRSLLEMYADYFAHPDLFIKISDLDDPRDRIVQVCRWYMSAY 485
            .||.|::.||||::||||||:||.||.|...:||:.|.||..:.:..:|...|:..|.|||:|.:
Human   373 TLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGF 437

  Fly   486 HAGRKSAVAKKPYNPILGEVFQCHWDIPGISQDAQEVRDGPVPWCRRDQLTF-LAEQVSHHPPIS 549
            :  :|....||||||||||.|:|.|..|                 :.|..|| :|||||||||:|
Human   438 Y--KKPKGIKKPYNPILGETFRCCWFHP-----------------QTDSRTFYIAEQVSHHPPVS 483

  Fly   550 AFYAEHYNKKITFAAHVWTKSKFLGLSIGVHNIGEGVVTLVDRSEEYIVTFPNGYGRSIL--TVP 612
            ||:..:.......:..:..||:|.|.|:.....|:..:|.::|:|:|.:|.|..:.:.||  |:.
Human   484 AFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMT 548

  Fly   613 WIELGGSVEIKCPQSGYYANVEFLTKPFYGGKR--NRVSAEVYAPSEKKPFVSITGEWSGLMEAK 675
             :||||.|.|:|.::.:.|.:||..|||:||..  |::|.::  .|.::...|::|.|...:..|
Human   549 -LELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVLASLSGHWDRDVFIK 610

  Fly   676 WHDKNKTEVF----VDVNRIPIFKKQVRPIVEQDEYESRRVWKEVTAGLKFNDIERATTAKFVVE 736
            ......:.:|    .:|.|..: ::...|:.||.|.||.|:|:.||..:...|..|||..||.:|
Human   611 EEGSGSSALFWTPSGEVRRQRL-RQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQEKFALE 674

  Fly   737 QQQRDQAKVRKEYDLAWEHK--HFKPVGDNWIY 767
            :.||.:|:.|:|..:.|:.:  |..|:...|.|
Human   675 EAQRQRARERQESLMPWKPQLFHLDPITQEWHY 707

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1513NP_610534.3 PH_ORP9 24..125 CDD:241444
Oxysterol_BP 421..767 CDD:460126 126/356 (35%)
OSBPL5NP_065947.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..73
PH_OPR5_ORP8 120..248 CDD:270103 17/69 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 254..341 15/86 (17%)
Oxysterol_BP 374..717 CDD:460126 127/357 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 742..806
Blue background indicates that the domain is not in the aligned region.

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