DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lsm11 and C49H3.4

DIOPT Version :9

Sequence 1:	NP_610522.1	Gene:	Lsm11 / 36013	FlyBaseID:	FBgn0033450	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001379819.1	Gene:	C49H3.4 / 183627	WormBaseID:	WBGene00016791	Length:	223	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	52/226 - (23%)
Similarity:	89/226 - (39%)	Gaps:	76/226 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 GDQGTSKKASTSE----AVDILPP--------ERRFEPHQMPTTSSRKKHHRNIFTYMEAAV--- 128
            |.:|.|:...|.|    .||:.|.        :.|....:...|.|:|:..|:....:||.:
Worm    24 GVEGNSEDFKTDEFEKNLVDLHPELAEEICDFDERTVREEKEKTISKKQQARDRQIRLEAMMTDG 88

  Fly   129 -------------------GPLELLTKCISPASHNESNERR---RVRVVIRKHGSVGGSVEGELL 171
                               ||:.::...:       .|::|   |||..||    :....||...
Worm    89 RSVIEKKGITFHDKMITIEGPMSMIANAV-------INQKRIEVRVRSAIR----IDRIFEGIPT 142

  Fly   172 AFDKQWNLLLRNVTET----WKRRKYNYGEQNICDTPVDCTGRLKELGITLPRTV---------V 223
            .||:.:||::::||||    .|.:|             :.|.| ||:.:.||..:         :
Worm   143 TFDEHFNLMMKDVTETVLHGRKAQK-------------EFTNR-KEMQLLLPEFLRWKEGGNWPM 193

  Fly   224 KNLNRKNVEIRRELPQILIRGENVVLVSLIP 254
            |....:.:|.|.: ....|:|::||||.::|
Worm   194 KVGTNRLIEHRFQ-RACFIKGDSVVLVRMLP 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lsm11	NP_610522.1	LSm11_M	<158..204	CDD:212485	12/49 (24%)
Lsm11	NP_610522.1	Sm_like	<166..252	CDD:294186	27/98 (28%)
C49H3.4	NP_001379819.1	Sm_like	120..221	CDD:412267	33/119 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165436
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_107358
Panther	1	1.100	-	-	LDO	PTHR21415
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930