DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lsm11 and lsm11

DIOPT Version :9

Sequence 1:	NP_610522.1	Gene:	Lsm11 / 36013	FlyBaseID:	FBgn0033450	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_017214640.2	Gene:	lsm11 / 100004030	ZFINID:	ZDB-GENE-050309-124	Length:	403	Species:	Danio rerio

Alignment Length:	317	Identity:	80/317 - (25%)
Similarity:	128/317 - (40%)	Gaps:	84/317 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ESRDRKTSNEDDSSEISELDVGSDRFNPLRALYEPNFRVTDAVPKV-IYQNLAAFESALKKFGIW 65
            ||..:....::|..| ::||:.||:|:||.|||.|  :|....|.: .:.|:|.:||.:|..
Zfish   102 ESTGQNPETDEDDVE-TKLDIRSDKFDPLLALYSP--QVPLPYPNIKCFNNIAEYESFMKGG--- 160

  Fly    66 QLNKRQKPGSAEGGDQGTSKKASTSEAVDIL-------PPERRFEPHQMPTTSSRKKHHRNIFTY 123
              ..|.||.:.|...:...|..:..|.::.|       |.....|...:.....::|..:|:.|.
Zfish   161 --RGRAKPENVEKRLRKAQKGKADPERIERLKRLMVNNPVPEEGEGSGVKRPPRQRKTAKNVLTR 223

  Fly   124 MEAAVG-PLELLTKCISPASHNESNERRRVRVVIRKHGSVGGSVEGELLAFDKQWNLLLRNVTET 187
            |....| ||..|.:|:        .|:.||:|.||....:.|...|.::||||.|||.:.:|.||
Zfish   224 MPLHTGSPLGQLNRCV--------QEKIRVKVHIRTFKGLRGVCSGFVVAFDKFWNLAMVDVDET 280

  Fly   188 WK----------------------------------RRKYNYGEQNICDTPVDCTGRLKELG--- 215
            ::                                  .||  .|::.:...|...:.:||:..
Zfish   281 YREPLLGQALYHEKALTITRLFEKLKVQETAALSAVERK--QGDKLLKSDPRSGSSQLKDQSRRS 343

  Fly   216 ----------------ITLPRTVVKNLNRKNVEI----RRELPQILIRGENVVLVSL 252
                            .|..|.:.|..:|..||.    .|.:.|:.||||||:||::
Zfish   344 DSRHNKEKPELSEIDKSTSSREMQKPESRPKVEYGRVHTRHVNQLFIRGENVLLVNI 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lsm11	NP_610522.1	LSm11_M	<158..204	CDD:212485	15/79 (19%)
Lsm11	NP_610522.1	Sm_like	<166..252	CDD:294186	33/142 (23%)
lsm11	XP_017214640.2	LSm11_M	235..300	CDD:212485	20/72 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593123
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CMUN
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	68	1.000	Inparanoid score	I5340
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1605022at2759
OrthoFinder	1	1.000	-	-		FOG0008244
OrthoInspector	1	1.000	-	-		oto39303
orthoMCL	1	0.900	-	-		OOG6_107358
Panther	1	1.100	-	-	LDO	PTHR21415
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4857
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.790