Protein Alignment Smyd4-1 and ZMYND15

DIOPT Version :10

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_047292879.1
• Gene: ZMYND15 / 84225
• HGNCID: 20997
• Length: 810
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 54/280 - (19%)
• Similarity: 99/280 - (35%)
• Gaps: 67/280 - (23%)

  Fly   122 NGSGSTSDSSNTLDAGSEE-EEEEEEHEKQPIFTDRGGGDADLNLDSDPSSQIIKVNIAHKKRVS 185
            |...|.|..:|.|.:.|.: :....|.:...:|.:          ...|....:.| :|.::.::
Human    30 NVGNSFSGPANPLVSRSNKFQNSSVEDDDDVVFIE----------PVQPPPPSVPV-VADQRTIT 83

  Fly   186 DPEAYKNWLKAKNEEIRKNREKELLAKQELQRQK----------EQEEEKRKEESKKKIKEWMER 240
                   :..:||||::.|..|...:.:||..||          ::|:.:..:..:|....::||
Human    84 -------FTSSKNEELQGNDSKITPSSKELASQKGSVSETIVIDDEEDMETNQGQEKNSSNFIER 141

  Fly   241 KKHDSTKKATNPKAAKERQHSQSS-----SSEHLYCDPDAKFKSWLLNVRKRE------------ 288
            :..: ||..||.........|:|.     .:..:..:||::.:  :.||...|
Human   142 RPPE-TKNRTNDVDFSTSSFSRSKVNAGMGNSGITTEPDSEIQ--IANVTTLETGVSSVNDGQLE 203

  Fly   289 ----EEKRLRAQTVKQLEKK--------IQDEKKKISGEIYQEWLKSAKHKPKPVPLNQGPHTLR 341
                .:..|....|..|:..        :|.....::.:.|...|.| :.|....|.|.|...:.
Human   204 NTDGRDMNLMITHVTSLQNTNLGDVSNGLQSSNFGVNIQTYTPSLTS-QTKTGVGPFNPGRMNVA 267

  Fly   342 GTV-----SQIFINPQPWKS 356
            |.|     |....||..|.|
Human   268 GDVFQNGESATHHNPDSWIS 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	9/44 (20%)
		zf-MYND	258..298	CDD:460312	8/60 (13%)
		SET	<359..549	CDD:394802
ZMYND15	XP_047292879.1	zf-MYND	381..427	CDD:460312
		MSS51_C	552..746	CDD:466330