DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Smyd4-1 and TPR9

DIOPT Version :9

Sequence 1:	NP_610500.2	Gene:	Smyd4-1 / 35985	FlyBaseID:	FBgn0033427	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_001321056.1	Gene:	TPR9 / 840233	AraportID:	AT1G33400	Length:	810	Species:	Arabidopsis thaliana

Alignment Length:	841	Identity:	174/841 - (20%)
Similarity:	271/841 - (32%)	Gaps:	309/841 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LQI-FQKLALDL------LQDLEQPVDRKGCA----ERSKNLREEGNLMFKESASGSSKDSVLKA 92
            ||: |..|:..|      :.:|..|  ..||.    |.|.:|:..||..|:      |:| ..:|
plant    39 LQLNFSSLSFSLVLLSQAVSELANP--ELGCCGKNEETSLDLKRRGNHCFR------SRD-FDEA 94

  Fly    93 CRLYSEAVFEAE-NAVEE----LSLAFANRGIALQEYGYYREAYDDCSNALECG--YPERLRHKV 150
            .||||:|:..|. :|::.    |:..|.||...|...|..:|:..||..||...  |.:
plant    95 LRLYSKALRVAPLDAIDGDKSLLASLFLNRANVLHNLGLLKESLRDCHRALRIDPYYAK------ 153

  Fly   151 IMRQAFCAW----KLKKIASLEEHLDYLGQLQLKESFEQQLEDLKQKLELLKNQPREQETQGKVV 211
                   ||    ||..:  |..:.|....:.:..|.|..|...||....||..|..|..|....
plant   154 -------AWYRRGKLNTL--LGNYKDAFRDITVSMSLESSLVGKKQLQNELKAIPDYQNNQTLEH 209

  Fly   212 DKSLGEILTDPG-------------------PRGRYMVAKEAISKGNVIFSER-------ASCFV 250
            |:....  .|.|                   .:||.||::..|.:.:||..|.       .||
plant   210 DEYRPS--NDAGVDHLPSVQMEVKLRCVSTKEKGRGMVSECDIEEASVIHVEEPFSVVISKSC-- 270

  Fly   251 PLEQLLICQQCAATLMSAPIPCPNCHQRVVYCSRKCR------------EAHSAIHKFECAAYRK 303
               :...|..|...|.:..:|||:| ...||||..|:            :.|....|..     .
plant   271 ---RETHCHFCLNELPADTVPCPSC-SIPVYCSESCQIQSGGMLSTNEMDKHHIFQKLP-----D 326

  Fly   304 DIL-RLLGISHLALRLLLTYIPYIRPHLQEMTSAKGMWE---------------EIMNLSRKPEE 352
            ||: .:.|::...:....|.:  |:.|..|...|.  |.               :::|..:...:
plant   327 DIVEHIKGVTSADIYYFATDL--IQEHQHECRGAN--WPAVLPSDAVLAGRIIMKLINQGKAATD 387

  Fly   353 SENAPEYLRSLRMVSQLDQAIDEELNYHILCANLLQLYLKEHTDFYDQFHSLP------ASIEDW 411
            ..|..|.|......|:::.  :.:|..|:|...|:....|.         |.|      ||:...
plant   388 LSNLQEILELSHTYSKMNP--ENKLELHLLSIVLIWCLSKS---------SCPNLSVCEASVTQT 441

  Fly   412 QLIISALILRFAGQLLANG-------HVGDALLGVGMEPKEFVMLQPELWQKPRHLKRGQLHNLS 469
            .:::|        |:..|.       ..||:.                     :.|..|   |:|
plant   442 IILLS--------QIKVNSIAVARMKSSGDSF---------------------KCLPSG---NIS 474

  Fly   470 HSDPITAINLPYL--------SLCNHACEPSIRTKF--------------DGCSVVNYAAKDILE 512
            ..:||.::....:        ||.||:|:|:|...|              .||.:      ::..
plant   475 TKEPIQSLEQIRVGQALYKTGSLFNHSCKPNIHLYFLSRGLIMQTTEFVPTGCPL------ELSY 533

  Fly   513 GEEIFNCYTMDYRNSLKLQRSHPLKAIYKFECTCAKCTRTDPDQNYLSFHRYRCEKPNCRQEFLP 577
            |.|:..   .|.:|.::.     |:..|.|.|.|..|.:.:...  |..:.|.|...||....|
plant   534 GPEVGK---WDCKNRIRF-----LEEEYFFHCRCRGCAQINISD--LVINGYGCVNTNCTGVVL- 587

  Fly   578 DAKVQQNNLRWWLRCNAEKPITCTVCHELQHFAWYNEFLGLIGSSADSSKRQALFKAFDDLDKWL 642
            |:.|        ..|.:||         |.||                      |.|..::|
plant   588 DSNV--------ATCESEK---------LNHF----------------------FTAPRNVD--- 610

  Fly   643 VDHHSLKRIMAEELVTACFYEIDGGTSLDEFEYEDLARIIRKQLE----------GIAAQCG--- 694
                  :::...|.|                 |.|:..:....|.          .|..:||
plant   611 ------QQVQMREKV-----------------YADVGEVASSLLSKPSGSLHIEPEICLKCGSRC 652

  Fly   695 --DNSTEYIARMTYLWDIIAQKKCRTDRKELLEMKGKVDY--LASEHREV-----FLNYYN 746
              :||.   |.:...|:       ...|.|.|...|:.:|  |:...|.:     ||:.||
plant   653 DIENSH---AEVNKAWN-------HMRRVEELMNSGRANYSVLSDCSRSIAVLRTFLHMYN 703

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	zf-MYND	258..298	CDD:280009	14/51 (27%)
Smyd4-1	NP_610500.2	SET	<447..526	CDD:214614	19/100 (19%)
TPR9	NP_001321056.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1278034at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820