Protein Alignment Smyd4-1 and TPR9

DIOPT Version :10

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001321056.1
• Gene: TPR9 / 840233
• AraportID: AT1G33400
• Length: 810
• Species: Arabidopsis thaliana
• Alignment Length: 841
• Identity: 174/841 - (20%)
• Similarity: 271/841 - (32%)
• Gaps: 309/841 - (36%)

  Fly    39 LQI-FQKLALDL------LQDLEQPVDRKGCA----ERSKNLREEGNLMFKESASGSSKDSVLKA 92
            ||: |..|:..|      :.:|..|  ..||.    |.|.:|:..||..|:      |:| ..:|
plant    39 LQLNFSSLSFSLVLLSQAVSELANP--ELGCCGKNEETSLDLKRRGNHCFR------SRD-FDEA 94

  Fly    93 CRLYSEAVFEAE-NAVEE----LSLAFANRGIALQEYGYYREAYDDCSNALECG--YPERLRHKV 150
            .||||:|:..|. :|::.    |:..|.||...|...|..:|:..||..||...  |.:
plant    95 LRLYSKALRVAPLDAIDGDKSLLASLFLNRANVLHNLGLLKESLRDCHRALRIDPYYAK------ 153

  Fly   151 IMRQAFCAW----KLKKIASLEEHLDYLGQLQLKESFEQQLEDLKQKLELLKNQPREQETQGKVV 211
                   ||    ||..:  |..:.|....:.:..|.|..|...||....||..|..|..|....
plant   154 -------AWYRRGKLNTL--LGNYKDAFRDITVSMSLESSLVGKKQLQNELKAIPDYQNNQTLEH 209

  Fly   212 DKSLGEILTDPG-------------------PRGRYMVAKEAISKGNVIFSER-------ASCFV 250
            |:....  .|.|                   .:||.||::..|.:.:||..|.       .||
plant   210 DEYRPS--NDAGVDHLPSVQMEVKLRCVSTKEKGRGMVSECDIEEASVIHVEEPFSVVISKSC-- 270

  Fly   251 PLEQLLICQQCAATLMSAPIPCPNCHQRVVYCSRKCR------------EAHSAIHKFECAAYRK 303
               :...|..|...|.:..:|||:| ...||||..|:            :.|....|..     .
plant   271 ---RETHCHFCLNELPADTVPCPSC-SIPVYCSESCQIQSGGMLSTNEMDKHHIFQKLP-----D 326

  Fly   304 DIL-RLLGISHLALRLLLTYIPYIRPHLQEMTSAKGMWE---------------EIMNLSRKPEE 352
            ||: .:.|::...:....|.:  |:.|..|...|.  |.               :::|..:...:
plant   327 DIVEHIKGVTSADIYYFATDL--IQEHQHECRGAN--WPAVLPSDAVLAGRIIMKLINQGKAATD 387

  Fly   353 SENAPEYLRSLRMVSQLDQAIDEELNYHILCANLLQLYLKEHTDFYDQFHSLP------ASIEDW 411
            ..|..|.|......|:::.  :.:|..|:|...|:....|.         |.|      ||:...
plant   388 LSNLQEILELSHTYSKMNP--ENKLELHLLSIVLIWCLSKS---------SCPNLSVCEASVTQT 441

  Fly   412 QLIISALILRFAGQLLANG-------HVGDALLGVGMEPKEFVMLQPELWQKPRHLKRGQLHNLS 469
            .:::|        |:..|.       ..||:.                     :.|..|   |:|
plant   442 IILLS--------QIKVNSIAVARMKSSGDSF---------------------KCLPSG---NIS 474

  Fly   470 HSDPITAINLPYL--------SLCNHACEPSIRTKF--------------DGCSVVNYAAKDILE 512
            ..:||.::....:        ||.||:|:|:|...|              .||.:      ::..
plant   475 TKEPIQSLEQIRVGQALYKTGSLFNHSCKPNIHLYFLSRGLIMQTTEFVPTGCPL------ELSY 533

  Fly   513 GEEIFNCYTMDYRNSLKLQRSHPLKAIYKFECTCAKCTRTDPDQNYLSFHRYRCEKPNCRQEFLP 577
            |.|:..   .|.:|.::.     |:..|.|.|.|..|.:.:...  |..:.|.|...||....|
plant   534 GPEVGK---WDCKNRIRF-----LEEEYFFHCRCRGCAQINISD--LVINGYGCVNTNCTGVVL- 587

  Fly   578 DAKVQQNNLRWWLRCNAEKPITCTVCHELQHFAWYNEFLGLIGSSADSSKRQALFKAFDDLDKWL 642
            |:.|        ..|.:||         |.||                      |.|..::|
plant   588 DSNV--------ATCESEK---------LNHF----------------------FTAPRNVD--- 610

  Fly   643 VDHHSLKRIMAEELVTACFYEIDGGTSLDEFEYEDLARIIRKQLE----------GIAAQCG--- 694
                  :::...|.|                 |.|:..:....|.          .|..:||
plant   611 ------QQVQMREKV-----------------YADVGEVASSLLSKPSGSLHIEPEICLKCGSRC 652

  Fly   695 --DNSTEYIARMTYLWDIIAQKKCRTDRKELLEMKGKVDY--LASEHREV-----FLNYYN 746
              :||.   |.:...|:       ...|.|.|...|:.:|  |:...|.:     ||:.||
plant   653 DIENSH---AEVNKAWN-------HMRRVEELMNSGRANYSVLSDCSRSIAVLRTFLHMYN 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	12/60 (20%)
		zf-MYND	258..298	CDD:460312	14/51 (27%)
		SET	<359..549	CDD:394802	41/224 (18%)
TPR9	NP_001321056.1	TPR	78..>182	CDD:440225	33/125 (26%)
		TPR repeat	78..103	CDD:276809	12/31 (39%)
		TPR repeat	108..147	CDD:276809	12/38 (32%)
		zf-MYND	275..>303	CDD:480929	11/28 (39%)
		SET	386..562	CDD:394802	43/232 (19%)
		TPR_12	705..781	CDD:315987