back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Smyd4-1 and SMYD3

DIOPT Version :9

Sequence 1:	NP_610500.2	Gene:	Smyd4-1 / 35985	FlyBaseID:	FBgn0033427	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_001161212.1	Gene:	SMYD3 / 64754	HGNCID:	15513	Length:	428	Species:	Homo sapiens

Alignment Length:	353	Identity:	80/353 - (22%)
Similarity:	130/353 - (36%)	Gaps:	110/353 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   216 GEILTDPGPRGRYMVAKEAISKGNVIFSERASCFVPLEQLLICQQCAATLMSAPIPCPNCHQRVV 280
            ||:|....|.. |.|.|.  |:|  :..:|  |.:..|:|:.|.||                ||.
Human    27 GELLFRSDPLA-YTVCKG--SRG--VVCDR--CLLGKEKLMRCSQC----------------RVA 68

  Fly   281 -YCSRKCREAHSAIHKFECAA-------YRKDILRLLGISHLALRLLLTYIPYIRPHLQEMTSAK 337
             |||.||::.....||.||..       |..|.:||||  .:..:|
Human    69 KYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLG--RVVFKL------------------- 112

  Fly   338 GMWEEIMNLSRKPEESENAPEYLRSLRMVSQLDQAIDEELNYHILCANLLQLYLKEHTDFYDQFH 402
                    :...|.|||....:......:::|.:...|.|...::   ..|.:::|......|
Human   113 --------MDGAPSESEKLYSFYDLESNINKLTEDKKEGLRQLVM---TFQHFMREEIQDASQ-- 164

  Fly   403 SLPASIEDWQLIISALILRFAGQLLANGHVGDALLGVGMEPKEFVMLQPELWQKPRHLKRGQLHN 467
             ||.:.:.::.....:...|.   :.|..:.:  :|||:.|.
Human   165 -LPPAFDLFEAFAKVICNSFT---ICNAEMQE--VGVGLYPS----------------------- 200

  Fly   468 LSHSDPITAINLPYLSLCNHACEPSIRTKFDGCSVVNYAAKDILEGEEIFNCYTMDYRNSLKLQR 532
                          :||.||:|:|:....|:|..::..|.:||..|||:..|| :|...:.: :|
Human   201 --------------ISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICY-LDMLMTSE-ER 249

  Fly   533 SHPLKAIYKFECTCAKCTRTDPDQNYLS 560
            ...|:..|.|||.|.:|...|.|.:.|:
Human   250 RKQLRDQYCFECDCFRCQTQDKDADMLT 277

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.