Protein Alignment Smyd4-1 and SmydA-3

DIOPT Version :10

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_609464.1
• Gene: SmydA-3 / 34502
• FlyBaseID: FBgn0262599
• Length: 507
• Species: Drosophila melanogaster
• Alignment Length: 517
• Identity: 96/517 - (18%)
• Similarity: 164/517 - (31%)
• Gaps: 182/517 - (35%)

  Fly   226 GRYMVAKEAISKGNVIFSERASCFVPLEQLLICQQCAATLMSAPIPCPNCHQ------------- 277
            |||:|||.||....::..|......|        :|     :.|:.|..|::
  Fly    21 GRYLVAKGAIRGHGLLIEELPFAVGP--------KC-----NGPVVCLGCYEPNPDPEEELCSEC 72

  Fly   278 ---RVVYCSRKCREAHSAIHKFECAAYRKDILRLL----GISH-------LALRLLLTYIPYIRP 328
               ..|.|:::...||   .:.||:..:....|..    |..|       :.||:||.
  Fly    73 GWPLCVECAQQADNAH---FRLECSQLKDARARFFRLPSGSRHCPQLDCIMPLRVLLA------- 127

  Fly   329 HLQEMTSAKGMWE-EIMNLSRKPEESENAPEYLRSLRMVSQLDQAIDEELNYHILCANLLQLYLK 392
              :|....:  |: |:..:....||.:.                  |.:: :|....|:.| ||:
  Fly   128 --KEANPER--WDNEVAPMEHHKEERQR------------------DADV-WHADRVNIAQ-YLR 168

  Fly   393 EHTDFYDQFHSLPASIEDWQLIISALILRFAGQLLANGHVGDALLGVGMEPKEFVMLQPELWQKP 457
            ......::|.             ..||::..|.|..|..       ....||.:
  Fly   169 GPCQLANRFS-------------EELIMQVVGVLEVNAF-------EARSPKGY----------- 202

  Fly   458 RHLKRGQLHNLSHSDPITAINLPYLSLCNHACEPSIRTKF---DGCSVVNYAAKDILEGEEIFNC 519
                           |:..: .||..:..|.|.|:.....   :|..:...|..|:.||:.:.:.
  Fly   203 ---------------PLRCL-FPYTGILAHNCVPNTSRSIYPSEGYKIRLRAMVDLEEGQPLHHS 251

  Fly   520 YTMDYRNSLKLQRSHPLKAIYKFECTCAKCTRTDPDQNYLSFHRYRCEKPNCRQEFLPDAKVQQN 584
            ||  |......||...||....|.|.|.:|  .||.:....|...:|.:  |.:.|....:..:.
  Fly   252 YT--YTLDGTAQRQKHLKQGKFFTCQCERC--LDPTELGTHFSSLKCGQ--CAEGFQVPRQPTEP 310

  Fly   585 NLRWWLRCNAEKPITCTVCHELQHFAWYNEFLGLIGSSADS-----------SKRQAL---FKAF 635
            :..|          .|..|             |...|:||:           :..|||   .|..
  Fly   311 DTSW----------NCANC-------------GSDTSNADALAMLQSLQSEVNAVQALPMAAKRL 352

  Fly   636 DDLDKWLVDHHS-----------LKRIMAEELVTACFYEIDGGTSLDEFEYEDLARIIRKQL 686
            :::::.|..:.|           |::::.|.......||:   ..|.:.:.|..|.:.|:.|
  Fly   353 EEIERLLRKYKSLLHPLHFIATGLRQLLIEMYGRVQGYEM---VQLPDHQLERKAELCRQVL 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	9/25 (36%)
		zf-MYND	258..298	CDD:460312	8/55 (15%)
		SET	<359..549	CDD:394802	35/192 (18%)
SmydA-3	NP_609464.1	SET_SMYD	<192..279	CDD:380997	24/122 (20%)