Protein Alignment Smyd4-1 and Smyd5

DIOPT Version :10

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001101340.1
• Gene: Smyd5 / 312503
• RGDID: 1309153
• Length: 417
• Species: Rattus norvegicus
• Alignment Length: 423
• Identity: 96/423 - (22%)
• Similarity: 139/423 - (32%)
• Gaps: 149/423 - (35%)

  Fly   225 RGRYMVAKEAISKGNVIFSER---ASCFV--PLEQLLICQQCAATLMSA---------------P 269
            :|:.:.|.:.|.||..||.||   ||.|:  .|.:...|..|...|..|               |
  Rat    32 KGKGLFATQLIRKGETIFIERPLVASQFLWNALYRYRACDHCLRALEKAEENAQRLTGKPGQVLP 96

  Fly   270 IP------------CPNCHQRVVYCSRKCR-EAHSAIHKFECAAYRKDILRLLGISHLALRLLLT 321
            .|            ||.|  :|.|||.:|| .|....|:..|....:|..|
  Rat    97 HPELCSVRKDLHQNCPRC--QVTYCSAECRLAAAEQYHQILCPGPSQDDPR-------------- 145

  Fly   322 YIPYIRPHLQEMTSAKGMWEEIMNLSRKPEESENAPEYLRSLRMVSQLDQAIDEELNYHILCANL 386
                     ..:...:..|..:    ..|.|:.:   .:...|||:.:.||.|
  Rat   146 ---------HPLNKLQEAWRSV----HYPPETAS---IMLMARMVATVKQAKD------------ 182

  Fly   387 LQLYLKEH-TDFYDQFHSLPASIEDWQLIISALILRFAGQLL----------------------- 427
                 |:| ...:..|.|..|: |:.:::...|..:|.|||.
  Rat   183 -----KDHWVRLFSHFCSKTAN-EEEEIVHKLLGDKFKGQLELLRRLFTEALYEETLSQWFTPDG 241

  Fly   428 ---------ANG------------HVGDALLGVGMEPKEFVMLQPELWQ--KPRHLKRGQLHNLS 469
                     .||            |..|||   .::|:|...|...:.|  |......|:..|..
  Rat   242 FRSLFALVGTNGQGIGTSSLSQWVHACDAL---ELKPQEREQLDTFIDQLYKDIEAATGEFLNCE 303

  Fly   470 HSDPITAINLPYLSLCNHACEPSIRTKFDGCSVVNY--AAKDILEGEEIFNCYTMDYRNSLKLQR 532
            .|....     ..|.|||:|.|:..|.|...:.:.:  |.:||..||||  |  :.|.:..:.:|
  Rat   304 GSGLFV-----LQSCCNHSCVPNAETSFPENNFLLHVTALEDIEPGEEI--C--ISYLDCCQRER 359

  Fly   533 SHP-----LKAIYKFECTCAKCTRTDPDQNYLS 560
            |..     |:..|.|.|:|.||.....|.|..|
  Rat   360 SRHSRHKILRENYLFVCSCPKCLAEADDPNVTS 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	12/31 (39%)
		zf-MYND	258..298	CDD:460312	17/67 (25%)
		SET	<359..549	CDD:394802	55/243 (23%)
Smyd5	NP_001101340.1	SET_SMYD5	22..384	CDD:380919	93/413 (23%)
		zf-MYND	101..136	CDD:480929	11/36 (31%)