Protein Alignment Smyd4-1 and Smyd1

DIOPT Version :10

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001100065.1
• Gene: Smyd1 / 297333
• RGDID: 1305105
• Length: 490
• Species: Rattus norvegicus
• Alignment Length: 493
• Identity: 103/493 - (20%)
• Similarity: 162/493 - (32%)
• Gaps: 176/493 - (35%)

  Fly   217 EILTDPGPRGRYMVAKEAISKGNVIFSERA---------------SCFVPLEQLLICQQCAATLM 266
            |:.|..| :||.:.|.:.....:|||:|||               :||...|:|..|.||..
  Rat    10 EVFTSEG-KGRGLKATKEFWAADVIFAERAYSAVVFDSLINFVCHTCFKRQERLHRCGQCKF--- 70

  Fly   267 SAPIPCPNCHQRVVYCSRKCREAHSAIHKFECAAYRKDILRLLGISHLALRLLLTYIPYIRPHLQ 331
                    .|    ||.|.|::.....||.||:|    |.|...:.:..:||
  Rat    71 --------AH----YCDRTCQKDAWLNHKNECSA----IKRYGKVPNENIRL------------- 106

  Fly   332 EMTSAKGMWEEIMNLSRKPEESENAPEYLRSLRMVSQLDQAI-----DEELNYHILCANLLQLYL 391
               :|:.||       |...|.....|  ..|..|..|...:     :|:....:.....||.:.
  Rat   107 ---AARIMW-------RVEREGTGLTE--GCLVSVDDLQNHVEHFGEEEQKELRVDVDTFLQYWP 159

  Fly   392 KEHTDFYDQFHSLPASIEDWQLIISALILRFAGQLLANGHV-----GDALLGVGMEPKEFVMLQP 451
            .:...|..|:                 |....|.:..||..     |...:|||:
  Rat   160 PQSQQFSMQY-----------------ISHIFGVINCNGFTLSDQRGLQAVGVGI---------- 197

  Fly   452 ELWQKPRHLKRGQLHNLSHSDPITAINLPYLSLCNHACEPSIRTKFDGCSVV----NY------- 505
                                       .|.|.|.||.|.|:       |:|:    |:
  Rat   198 ---------------------------FPNLGLVNHDCWPN-------CTVIFNNGNHEAVKSMF 228

  Fly   506 ---------AAKDILEGEEIFNCYTMDYRNSLKL--QRSHPLKAIYKFECTCAKCTRTDPDQNYL 559
                     |...|.||||:    |:.|.:.|.|  :|...||..|.|:|:|..|.:...|..:|
  Rat   229 HTQMRIELRALGKISEGEEL----TVSYIDFLHLSEERRQQLKKQYYFDCSCEHCQKGLKDDLFL 289

  Fly   560 SFHRYRCEKPNCRQEFLPD-AKVQQNNLRWWLRCNAEKPI-----TCTVCHELQHFAWYNEFLGL 618
            :..    |.|...||.:.: .:..::.|....:..:|...     .|..|.|.|...:.:..|.:
  Rat   290 AVK----EDPKPSQEVVKEMTQFSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNLYV 350

  Fly   619 IGSSADSSKRQALFKAFDDLDKW---LVD------HHS 647
            :...:..|:..:..:||::...:   :||      ||:
  Rat   351 LRLLSIVSEVLSYLQAFEEASHYARRMVDGYMKLYHHN 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	14/49 (29%)
		zf-MYND	258..298	CDD:460312	10/39 (26%)
		SET	<359..549	CDD:394802	43/221 (19%)
Smyd1	NP_001100065.1	SET_SMYD1	7..281	CDD:380924	83/380 (22%)
		zf-MYND	52..90	CDD:460312	14/52 (27%)