Protein Alignment Smyd4-1 and Smyd2

DIOPT Version :10

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_996733.1
• Gene: Smyd2 / 289372
• RGDID: 727785
• Length: 433
• Species: Rattus norvegicus
• Alignment Length: 467
• Identity: 96/467 - (20%)
• Similarity: 166/467 - (35%)
• Gaps: 154/467 - (32%)

  Fly   225 RGRYMVAKEAISKGNVIFS-----------ERA----SCFVPLEQLLICQQCAATLMSAPIPCPN 274
            :||.:.|......|:::||           ||.    .||...|.|..|.:|
  Rat    17 KGRGLRALRPFHVGDLLFSCPAYACVLTVGERGHHCECCFARKEGLSKCGRC------------- 68

  Fly   275 CHQRVVYCSRKCREAHSAIHKFECAAYRKDILRLLGISHLALRLLLTYIPYIRPHLQEMTSAKGM 339
              ::..||..:|::....:||.||::                  ::.:.....|......:|:.:
  Rat    69 --KQAFYCDVECQKEDWPLHKLECSS------------------MVVFGENWNPSETVRLTARIL 113

  Fly   340 WEEIMNLSRKPEESENAPEYLRSLRMVSQLDQAIDEELNYHIL--CANLLQLYLKEHTDFYDQFH 402
            .::.|:..|.|.|     :.|......|.||: :|.|....|.  .|.|.|.|.| |.:|.|.
  Rat   114 AKQKMHPERTPSE-----KLLAVREFESHLDK-LDNEKKDLIQSDIAALHQFYSK-HLEFPDH-- 169

  Fly   403 SLPASIEDWQLIISALILRFAGQLLANGHVGDALLGVGMEPKEFVMLQPELWQKPRHLKRGQLHN 467
                         |:|::.|| |:..||..        :|.:|
  Rat   170 -------------SSLVVLFA-QVNCNGFT--------IEDEE---------------------- 190

  Fly   468 LSHSDPITAINLPYLSLCNHACEPSIRTKFDGCSVVNYAAKDILEGEEIFNCY------TMDYRN 526
            |||   :.:...|.::|.||:|.|::...:.|......|.::|..|:|:|..|      |.|
  Rat   191 LSH---LGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIHPGDEVFTSYIDLLYPTED--- 249

  Fly   527 SLKLQRSHPLKAIYKFECTCAKCTRTDPDQNYLSFHRYRCEKPNCRQEFLPDAKVQQNNLRWWLR 591
                 |:..|:..|.|.|.|.:||..|.|:..:...  :...|       |.|:..::.:|:
  Rat   250 -----RNDRLRDSYFFTCECRECTTKDKDKAKVEIR--KLSNP-------PQAEAIRDMVRY--- 297

  Fly   592 CNAEKPITCTVCHEL---QHFAWYNEFLGLIGSSADSSKRQALFKAFDDLDKWLVDHHSLKRIMA 653
                   ...|..|.   :|:...:|.|.:...|     ::.:...|:|.:.:::  |.:.:.|.
  Rat   298 -------ARNVIEEFRRAKHYKSPSELLEICELS-----QEKMSSVFEDSNVYML--HMMYQAMG 348

  Fly   654 EELVTACFYEID 665
                 .|.|..|
  Rat   349 -----VCLYMQD 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	10/41 (24%)
		zf-MYND	258..298	CDD:460312	7/39 (18%)
		SET	<359..549	CDD:394802	48/197 (24%)
Smyd2	NP_996733.1	SET_SMYD2	7..269	CDD:380979	76/348 (22%)
		zf-MYND	52..90	CDD:460312	11/52 (21%)
		TPR_10	388..422	CDD:463861