Protein Alignment Smyd4-1 and SmydA-1

DIOPT Version :10

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_309979.5
• Gene: SmydA-1 / 1271226
• VectorBaseID: AGAMI1_002584
• Length: 534
• Species: Anopheles gambiae
• Alignment Length: 526
• Identity: 110/526 - (20%)
• Similarity: 176/526 - (33%)
• Gaps: 161/526 - (30%)

  Fly   226 GRYMVAKEAISKGNVIFSERASCFVPLEQLL--ICQQCAATLMSAP-IPCPNCHQRVVYCSRKCR 287
            ||::||...|..|.::..|......| .|:.  :|..|...|.... :.|..|...|  |.|.|:
Mosquito    62 GRFLVATRDIKAGEIVLKESPLVHGP-AQITGPVCVGCLQGLEEKKYLDCERCGWPV--CKRSCQ 123

  Fly   288 E--AHSAIHKFECAAYRKDILRLLGISHLALRLLLTYIPY-----IRP----HLQEMTSAKGMWE 341
            :  :|.|..||..|...|     :.|.|.       |:|:     :.|    .|.|...|:  ||
Mosquito   124 DSPSHQAECKFTIARGSK-----ISIQHF-------YVPHPTYQCLMPVRCLLLAESDPAR--WE 174

  Fly   342 EIMNLSRKPEESENAPEYLRSLRMVSQLDQAIDEELNYHILCANLLQLYLKEHTDFYDQFHSLPA 406
            .::.|....||...:.::......|::|       :.....|.|
Mosquito   175 TLLKLESHEEERRGSEQWRNDREGVAKL-------IPRFFKCEN--------------------- 211

  Fly   407 SIEDWQLIISALILRFAGQLLANGHVGDALLGVGMEPKEFVMLQPELWQKPRHLKRGQLHNLSHS 471
               .|.   ...|||..|.:..|||             |..|.:|         ....::|::
Mosquito   212 ---KWD---EDEILRVVGIIQVNGH-------------EVPMTEP---------SSVAIYNMA-- 246

  Fly   472 DPITAINLPYLSLCNHACEPSIRTKF-DGCSVVNYAAKDILEGEEIFNCYT-MDYRNSLKLQRSH 534
                       |:..|:|.|::...| :...||.:|...|..|:.:..||| :.:....:|:.
Mosquito   247 -----------SMLEHSCRPNLAKSFTNRGEVVMWAPNPIRRGDRLSICYTDVLWTTGNRLEH-- 298

  Fly   535 PLKAIYKFECTCAKCTRTDPDQNYLSFHRYRC----EKPNCRQEFLPDAKVQQNNLRW---W--L 590
             |:....|.|.|.:|:.....:.|  |...||    :...|:...||     .:|.:|   |  |
Mosquito   299 -LQQTKMFRCECERCSDRTEYETY--FSAVRCSGFQKDSKCKGFLLP-----VDNAQWTGEWQCL 355

  Fly   591 RCNAEKPITCTVCHELQHFAWYNEFLGLIGSSADSSKRQALFKAFDDLDKWLVDHHSLKRIMAEE 655
            ||:.|.. ..|||..|:......|       :.:..:.....:......|||..:|   :.|.:
Mosquito   356 RCSKEVS-GATVCQILERARMDLE-------AMEKHREDHCNRYMKHYSKWLTANH---QYMVD- 408

  Fly   656 LVTACFYEIDGG---TSLDEFEYE----------DLARIIRK--------------QLEGIAAQC 693
             |.....::.||   .::.:..||          ||..:..|              :|....|:.
Mosquito   409 -VKISLSQVIGGKNPEAIKKIPYEKLMNKIKICQDLIALFEKICPAEARAFGATRFELHAALAEL 472

  Fly   694 GDNSTE 699
            |..|||
Mosquito   473 GRRSTE 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	7/25 (28%)
		zf-MYND	258..298	CDD:460312	13/42 (31%)
		SET	<359..549	CDD:394802	34/191 (18%)
SmydA-1	XP_309979.5	None