Protein Alignment: Smyd4-1 and Smyd1

• Sequence 1: NP_610500.2
• Gene: Smyd4-1
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001153599.1
• Gene: Smyd1
• MGIID: 104790
• Length: 490
• Species: Mus musculus
• Alignment Length: 500
• Identity: 103/500 (21%)
• Similarity: 159/500 (32%)
• Gaps: 190/500 (38%)

  Fly   217 EILTDPGPRGRYMVAKEAISKGNVIFSERA---------------SCFVPLEQLLICQQCAATLM 266
            |:.|..| :||.:.|.:.....:|||:|||               :||...|:|..|.||..
Mouse    10 EVFTSEG-KGRGLKATKEFWAADVIFAERAYSAVVFDSLINFVCHTCFKRQEKLHRCGQCKF--- 70

  Fly   267 SAPIPCPNCHQRVVYCSRKCREAHSAIHKFECAAYRKDILRLLGISHLALRLLLTYIPYIR-PHL 330
                    .|    ||.|.|::.....||.||||.:|                     |.: |:.
Mouse    71 --------AH----YCDRTCQKDAWLNHKNECAAIKK---------------------YGKVPNE 102

  Fly   331 QEMTSAKGMWEEIMNLSRKPEESENAPEYLRSLRMVSQLDQAI-----DEELNYHILCANLLQLY 390
            ....:|:.||       |...|.....|  ..|..|..|...:     :|:....:.....||.:
Mouse   103 NIRLAARIMW-------RVEREGTGLTE--GCLVSVDDLQNHVEHFGEEEQKELRVDVDTFLQYW 158

  Fly   391 LKEHTDFYDQFHSLPASIEDWQLIISALILRFAGQLLANGHV-----GDALLGVGMEPKEFVMLQ 450
            ..:...|..|:                 |....|.:..||..     |...:|||:
Mouse   159 PPQSQQFSMQY-----------------ISHIFGVINCNGFTLSDQRGLQAVGVGI--------- 197

  Fly   451 PELWQKPRHLKRGQLHNLSHSDPITAINLPYLSLCNHACEPSIRTKFDGCSVV----NY------ 505
                                        .|.|.|.||.|.|:       |:|:    |:
Mouse   198 ----------------------------FPNLGLVNHDCWPN-------CTVIFNNGNHEAVKSM 227

  Fly   506 ----------AAKDILEGEEIFNCYTMDYRNSLKL--QRSHPLKAIYKFECTCAKCTRTDPDQNY 558
                      |...|.||||:    |:.|.:.|.|  :|...||..|.|:|:|..|.:...|..:
Mouse   228 FHTQMRIELRALGKISEGEEL----TVSYIDFLHLSEERRRQLKKQYYFDCSCEHCQKGLKDDLF 288

  Fly   559 LSFHRYRCEKPNCRQEFLPDA------------KVQQNNLRWWLRCNAEKPITCTVCHELQHFAW 611
            |:..    |.|...||.:.:.            |.:...|      ..|....|..|.|.|...:
Mouse   289 LAAK----EDPKPSQEVVKEMIQFSKDTLEKIDKARSEGL------YHEVVKLCRECLEKQEPVF 343

  Fly   612 YNEFLGLIGSSADSSKRQALFKAFDDLDKW---LVD------HHS 647
            .:..|.::...:.:|:..:..:|:::...:   :||      ||:
Mouse   344 ADTNLYVLRLLSIASEVLSYLQAYEEASHYARRMVDGYMKLYHHN 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	zf-MYND	258..298	CDD:280009	11/40 (28%)
		SET	<447..526	CDD:214614	18/99 (18%)
Smyd1	NP_001153599.1	S-adenosyl-L-methionine binding	17..19		1/2 (50%)
		zf-MYND	52..90	CDD:280009	15/53 (28%)
		SET	<194..257	CDD:214614	22/111 (20%)
		S-adenosyl-L-methionine binding	205..206		1/1 (100%)
		S-adenosyl-L-methionine binding. {ECO:0000250}	270..272		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C56269844
eggNOG	1	0.900				E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830