Protein Alignment Smyd4-1 and Smyd1

DIOPT Version :8

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001153599.1
• Gene: Smyd1 / 12180
• MGIID: 104790
• Length: 490
• Species: Mus musculus
• Alignment Length: 500
• Identity: 103/500 - (20%)
• Similarity: 159/500 - (31%)
• Gaps: 190/500 - (38%)

  Fly   217 EILTDPGPRGRYMVAKEAISKGNVIFSERA---------------SCFVPLEQLLICQQCAATLM 266
            |:.|..| :||.:.|.:.....:|||:|||               :||...|:|..|.||..
Mouse    10 EVFTSEG-KGRGLKATKEFWAADVIFAERAYSAVVFDSLINFVCHTCFKRQEKLHRCGQCKF--- 70

  Fly   267 SAPIPCPNCHQRVVYCSRKCREAHSAIHKFECAAYRKDILRLLGISHLALRLLLTYIPYIR-PHL 330
                    .|    ||.|.|::.....||.||||.:|                     |.: |:.
Mouse    71 --------AH----YCDRTCQKDAWLNHKNECAAIKK---------------------YGKVPNE 102

  Fly   331 QEMTSAKGMWEEIMNLSRKPEESENAPEYLRSLRMVSQLDQAI-----DEELNYHILCANLLQLY 390
            ....:|:.||       |...|.....|  ..|..|..|...:     :|:....:.....||.:
Mouse   103 NIRLAARIMW-------RVEREGTGLTE--GCLVSVDDLQNHVEHFGEEEQKELRVDVDTFLQYW 158

  Fly   391 LKEHTDFYDQFHSLPASIEDWQLIISALILRFAGQLLANGHV-----GDALLGVGMEPKEFVMLQ 450
            ..:...|..|:                 |....|.:..||..     |...:|||:
Mouse   159 PPQSQQFSMQY-----------------ISHIFGVINCNGFTLSDQRGLQAVGVGI--------- 197

  Fly   451 PELWQKPRHLKRGQLHNLSHSDPITAINLPYLSLCNHACEPSIRTKFDGCSVV----NY------ 505
                                        .|.|.|.||.|.|:       |:|:    |:
Mouse   198 ----------------------------FPNLGLVNHDCWPN-------CTVIFNNGNHEAVKSM 227

  Fly   506 ----------AAKDILEGEEIFNCYTMDYRNSLKL--QRSHPLKAIYKFECTCAKCTRTDPDQNY 558
                      |...|.||||:    |:.|.:.|.|  :|...||..|.|:|:|..|.:...|..:
Mouse   228 FHTQMRIELRALGKISEGEEL----TVSYIDFLHLSEERRRQLKKQYYFDCSCEHCQKGLKDDLF 288

  Fly   559 LSFHRYRCEKPNCRQEFLPDA------------KVQQNNLRWWLRCNAEKPITCTVCHELQHFAW 611
            |:..    |.|...||.:.:.            |.:...|      ..|....|..|.|.|...:
Mouse   289 LAAK----EDPKPSQEVVKEMIQFSKDTLEKIDKARSEGL------YHEVVKLCRECLEKQEPVF 343

  Fly   612 YNEFLGLIGSSADSSKRQALFKAFDDLDKW---LVD------HHS 647
            .:..|.::...:.:|:..:..:|:::...:   :||      ||:
Mouse   344 ADTNLYVLRLLSIASEVLSYLQAYEEASHYARRMVDGYMKLYHHN 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	zf-MYND	258..298	CDD:280009	10/39 (26%)
		SET	<447..526	CDD:214614	18/98 (18%)
Smyd1	NP_001153599.1	S-adenosyl-L-methionine binding	17..19		0/1 (0%)
		zf-MYND	52..90	CDD:280009	14/52 (27%)
		SET	<194..257	CDD:214614	21/110 (19%)