Protein Alignment Myd88 and myd88

DIOPT Version :10

• Sequence 1: NP_610479.1
• Gene: Myd88 / 35956
• FlyBaseID: FBgn0033402
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_997979.2
• Gene: myd88 / 403145
• ZFINID: ZDB-GENE-040219-3
• Length: 284
• Species: Danio rerio
• Alignment Length: 302
• Identity: 76/302 - (25%)
• Similarity: 137/302 - (45%)
• Gaps: 41/302 - (13%)

  Fly    82 PLSALGIETRTQLSRMLNRKKVLRSEEGYQRDWRGISEL-----AKQKGFVDENANNPMDLVLIS 141
            |::||....|.:|...||....:.:      |||.::||     .:.|.|  |..:.|.:.||..
Zfish    13 PVTALNCSFRKKLGLFLNPTNTVAA------DWRTVAELMDFTYLEIKNF--EKRDCPFEKVLTD 69

  Fly   142 WSQRSPQTAKVGHLEHFLGIIDRWDVCDDIQENLAKDTQRFIMKQEQR--QTALVEACPPPPSDC 204
            |..|...|  |.:|...|...:|.||..:::|.|..|.::::.:|:::  |..:|::|.|...:
Zfish    70 WETRPDAT--VANLLSILEKAERKDVISELKEILDDDCRKYMERQQRKPLQVPVVDSCGPRTQE- 131

  Fly   205 FETNNNYSSSNNITVGQSVQILSDEDQRCVQMGQPLPRYNACVLYAEADIDHATEIMNNLESERY 269
                     ...:|:....|.|:.|            .::|.:.|.::||....|::..||...|
Zfish   132 ---------REGVTLYDDPQGLTPE------------TFDAFICYCQSDIQFVHEMIKQLEHTEY 175

  Fly   270 NLRLFLRHRDMLMGVPFEHVQLSHFMATRCNHLIVVLTEEFLRSPENTYLVNFTQKIQIENHTRK 334
            ||:|.:..||:|.|.....: .|..:..||..::||:::::|.|....:...|...:.....|::
Zfish   176 NLKLCVFDRDVLPGTCVWTI-ASELIEKRCKRMVVVISDDYLDSDACDFQTKFALSLCPGARTKR 239

  Fly   335 IIPILYKT-DMHIPQTLGIYTHIKYAGDSKLFNFWDKLARSL 375
            :||::||: ....|..|...|...|:.......||.:||::|
Zfish   240 LIPVVYKSMKRPFPSILRFLTICDYSKPCTQVWFWTRLAKAL 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myd88	NP_610479.1	DD	90..172	CDD:472698	24/86 (28%)
		SEFIR	242..375	CDD:474043	36/133 (27%)
myd88	NP_997979.2	Death_MyD88	21..98	CDD:260026	24/86 (28%)
		Intermediate domain. /evidence=ECO:0000250	102..143		7/50 (14%)
		TIR	148..284	CDD:214587	37/135 (27%)