Protein Alignment hig and Cd55

DIOPT Version :10

• Sequence 1: NP_724773.1
• Gene: hig / 35949
• FlyBaseID: FBgn0010114
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: NP_001391888.1
• Gene: Cd55 / 13136
• MGIID: 104850
• Length: 471
• Species: Mus musculus
• Alignment Length: 273
• Identity: 78/273 - (28%)
• Similarity: 104/273 - (38%)
• Gaps: 84/273 - (30%)

  Fly   682 IKNIENNDSGTF---TCTSPRGLTNSIAVVVATSTCPQLTEPLAPLK---LRLEGNKLGQRAHYE 740
            ::|.:.:...||   :|.:|..|:                  .|.||   |.:....:|....||
Mouse    82 LENGQWSSHETFCEKSCVAPERLS------------------FASLKKEYLNMNFFPVGTIVEYE 128

  Fly   741 CPEGFR----LDGAWNATCLASGNWSSPTPTCHAIQCPR-LELDDPHLSL-------IELNTSAW 793
            |..|||    |.|  .||||....||.....|....||. .:||:.|:::       .|:|
Mouse   129 CRPGFRKQPPLPG--KATCLEDLVWSPVAQFCKKKSCPNPKDLDNGHINIPTGILFGSEIN---- 187

  Fly   794 GRAVFKCQWGFKLTGPAQLDCEPSG---VWSGPVPRCKVIQCVMPVAPLNGRIGGTSLSQRRLTV 855
                |.|..|::|.|.:...|..:|   .|....|.|..|.|..|....||.:.|.|.|   .|.
Mouse   188 ----FSCNPGYRLVGVSSTFCSVTGNTVDWDDEFPVCTEIHCPEPPKINNGIMRGESDS---YTY 245

  Fly   856 GALVTFSCNDGHSLVGESSIICT----ENGQWSHSPPFC--KSQ--------------------- 893
            ..:||:||:.|..|||.:||.||    :.||||..||.|  ||:
Mouse   246 SQVVTYSCDKGFILVGNASIYCTVSKSDVGQWSSPPPRCIEKSKVPTKKPTINVPSTGTPSTPQK 310

  Fly   894 -----CPYPGDPP 901
                 .|.|||.|
Mouse   311 PTTESVPNPGDQP 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hig	NP_724773.1	Ig_3	612..696	CDD:464046	3/16 (19%)
		PHA02927	705..952	CDD:222943	72/247 (29%)
Cd55	NP_001391888.1	CCP	36..95	CDD:153056	3/12 (25%)
		PHA02927	98..>292	CDD:222943	70/224 (31%)
		PI3K_1B_p101	<211..>449	CDD:463109	38/116 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	273..362		14/51 (27%)