Protein Alignment hig and arc3

DIOPT Version :10

• Sequence 1: NP_724773.1
• Gene: hig / 35949
• FlyBaseID: FBgn0010114
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: NP_001120599.1
• Gene: arc3 / 100145756
• XenbaseID: XB-GENE-6454074
• Length: 562
• Species: Xenopus tropicalis
• Alignment Length: 528
• Identity: 122/528 - (23%)
• Similarity: 181/528 - (34%)
• Gaps: 168/528 - (31%)

  Fly   547 LLSNTEINVGWDLPHGHSLQARCQE-LGIYKLLGESR-VLCSNGL-WAPRMPSCVPTTVLTNYSE 608
            ||....|: |...|...|:...|.: .|.|::.|.|| :.|.:.. |:.....|:...
 Frog    34 LLHTVPID-GKSFPVDESVVYSCNKTAGYYEIPGRSRTITCQDDFTWSTVPEFCIRAC------- 90

  Fly   609 DSAP----------SIRIKIF-NGSHSFEPSGVMAVPPHSTVLMDCM--YPRVRGT-------PE 653
            ||.|          .|...|: ||               :||..||.  |.|:.||       ..
 Frog    91 DSPPRLDFAQLGQEDINKNIYLNG---------------TTVKYDCRPGYKRIPGTDRTISCLDN 140

  Fly   654 WSWT---SWYMQYSTG---------WSPAQEE----KAVR------YRLSIKNIEN--NDSGTFT 694
            ::||   |:..:.|.|         :.|...|    ..|.      ||:..|.:..  ...|.::
 Frog   141 FTWTAPQSFCQRRSCGHPGEIDNGEFEPTDSEFLFGSTVTYKCNEGYRMISKQLSKTCKSDGKWS 205

  Fly   695 CTSPRGLTNSIAVVVATSTCPQLTEPLAP-------LKLRLEGNKLGQRAHYECPEGFRLDGAWN 752
            .:.|:     ..|:|.|          ||       .|.:.|.....:...|.|...|.|.|..:
 Frog   206 ISFPQ-----CEVMVCT----------APGDINDGFYKPQKEEYHYQEAVTYGCNNNFALIGNRS 255

  Fly   753 ATCLASGNWSSPTPTCHAIQCPRLELDDPHLSLIELNTSAWGRAV-FKCQWGFKLTGPAQLDCEP 816
            |.|.:.|.|||..|.|..::||...:.:...|...|.......|| |||..||.:.|...:.|..
 Frog   256 AYCTSDGTWSSQAPVCKDVKCPEPNVPNARKSSGFLGPYLLRSAVSFKCDEGFMMNGSDIIKCNV 320

  Fly   817 SGVWSGPVPRCKVIQCVMP---VAPL-------NGRIGGTSLS-------QRRL----TVGALVT 860
            ...|. |:|.| :..|.:|   .|.|       .|...||:|.       :.||    |:..|.|
 Frog   321 ENQWD-PLPEC-LRFCTLPSLEYAKLREKYSNRKGFFAGTTLEYDCLPGHRLRLNTEPTIKCLDT 383

  Fly   861 FS---------------------------------------CNDGHSLVGESSIICTENGQWSHS 886
            |.                                       |::|:: ...:.:.|..:|.||:.
 Frog   384 FQWSSMKTSCEQIVCEHPQDFSKGRINTQGPYKYQTRVTVICDEGYT-TKTNHLECQIDGTWSNY 447

  Fly   887 PPFCKS-QCPYPGDPPNGLI---APLKFNYDAGDYLSVQCRPGFVQSYEGPPERPKCQPDGRWSG 947
            ||.|:. .|.:||:..||.|   .|.|:|    ..::..|..|    |.......:|:.||.||.
 Frog   448 PPVCEEIVCKHPGEFSNGKIDTQGPYKYN----TKVTFICNEG----YTAKTSHLECKIDGTWSN 504

  Fly   948 PMPKCKSY 955
            ..|.|:::
 Frog   505 YPPVCEAH 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hig	NP_724773.1	Ig_3	612..696	CDD:464046	25/127 (20%)
		PHA02927	705..952	CDD:222943	78/318 (25%)
arc3	NP_001120599.1	CCP	28..87	CDD:153056	14/53 (26%)
		PHA02927	86..332	CDD:222943	66/284 (23%)
		PHA02927	331..>510	CDD:222943	41/187 (22%)