Protein Alignment VhaAC45 and atp6ap1

DIOPT Version :10

• Sequence 1: NP_610470.1
• Gene: VhaAC45 / 35944
• FlyBaseID: FBgn0262515
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: XP_004913049.1
• Gene: atp6ap1 / 100487454
• XenbaseID: XB-GENE-952452
• Length: 454
• Species: Xenopus tropicalis
• Alignment Length: 477
• Identity: 101/477 - (21%)
• Similarity: 168/477 - (35%)
• Gaps: 130/477 - (27%)

  Fly     1 MLWKSLIALCVIGAAVA-----EQTPVFLWGANS---VAKPSL---KTVSQVEFAEQLAALLEDH 54
            ||....:.||:..|.::     ...||.:|....   ..||::   ...|:.||.:    ||:..
 Frog     1 MLLPFWLLLCLCFAFISAVMPMSHVPVLIWSTERSFLKVKPTVHGGHITSEHEFHK----LLDPE 61

  Fly    55 M------VVAFEENGLSSKDFLCSNSQAQSCYAQLQGVSPKTYYTSV---ENPSE-ALRSVAAKR 109
            .      ::.|.:..||.:||        :.|:.|.|.....:...|   .:||. .:.:|..|.
 Frog    62 FTATPKTIILFLQETLSMEDF--------TYYSSLSGSEGTMHNVKVLMNSSPSSLVIPAVNWKT 118

  Fly   110 EH------------NSIDASGKLTTPA---KCAVGTALFVTFEDAAESRE----ASLESHDAAIA 155
            .|            |.|.|...|:..:   |......:.|..:....|..    .:...:|..|.
 Frog   119 IHHLPGYIKNRGKWNIIRADQNLSISSVELKTEKSNLIIVKLQPLPRSSNIAAAKAFSENDKLIG 183

  Fly   156 AISKQ-----------------------FE--CKVAYLYLAAPSTAPVVQRRTRRDTAATTGGIM 195
            .::|:                       ||  .|:.....:..:|||.........||..
 Frog   184 RLTKELIKRDIDFTGIYTGMKPSKVLQTFEMTAKIGRQLQSIGTTAPYPPLNVTNGTATC----- 243

  Fly   196 WKSTNQFQIFYTALLYNGNPITVTDL-------KLTNS-------SSTKLSVVMDT------SVA 240
                  ..|:.|.:|...|...|.||       |..|:       |:|.||::..:      |:.
 Frog   244 ------ILIYATQILITANNSQVFDLTNVTFEAKTANTSLSTCSQSNTTLSLLYSSPGNGLRSLE 302

  Fly   241 DKPITFDVVYNG---GYFSLSN--LVYDNNNFRSSGVN-----APTTFSYSCGNLTLESAAVNNM 295
            .:.:..:..|.|   .:|.|.:  ::.|.:..|.:..|     ||..:||.|..:...||....:
 Frog   303 IRFVMTNQFYTGSARNWFMLESIEIIPDGDESRIATFNTAYGSAPAEYSYHCQQIGTSSAYGEQL 367

  Fly   296 YNTLS--------FKSLQLQAPFDGTYKEDFPFGDSWDCVGFVTPGILMGLFVVALLLVIMFVGV 352
            ..:.|        ....|:|    |...::..|..:.||..|.||.|.|||....:||.|:..|:
 Frog   368 VRSNSQAGSWNIFISEFQIQ----GFNIQNNLFSYASDCTSFFTPAIWMGLVSSIVLLWILSYGI 428

  Fly   353 CWMMDINTMDRFDDPKGKTITI 374
            ..:|.:.|..:||||||:.:::
 Frog   429 FMIMQLTTNGKFDDPKGQQLSV 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VhaAC45	NP_610470.1	Lamp	211..309	CDD:480752	28/135 (21%)
		Ac45-VOA1_TM	328..366	CDD:466669	14/37 (38%)
atp6ap1	XP_004913049.1	VAS1_LD	242..389	CDD:461752	31/161 (19%)
		Ac45-VOA1_TM	404..442	CDD:466669	14/37 (38%)