Protein Alignment VhaAC45 and atp6ap1.2

DIOPT Version :10

• Sequence 1: NP_610470.1
• Gene: VhaAC45 / 35944
• FlyBaseID: FBgn0262515
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_001123842.1
• Gene: atp6ap1.2 / 100170603
• XenbaseID: XB-GENE-997187
• Length: 455
• Species: Xenopus tropicalis
• Alignment Length: 467
• Identity: 112/467 - (23%)
• Similarity: 182/467 - (38%)
• Gaps: 114/467 - (24%)

  Fly     3 WKSLIALCVIG---AAVAEQTPVFLWGANSV---AKPSLKT---VSQVEFAEQLAALLE--DHMV 56
            |..|..|.::|   ||.::|.||.||.:.|.   ::||:.:   .:..|....|...|.  ...:
 Frog     4 WALLSLLFLVGLFPAAPSQQVPVLLWSSESSVWNSQPSIHSGHIATDTELQRYLGPALTKGPRNL 68

  Fly    57 VAFEENGLSSKDF-----LCSNSQAQSCYAQLQGV---SPKT-------YYTSVENPSEALRSVA 106
            :.|.::.||.:||     :..|.| .|.:..||.:   ||.:       :|.:...|:.....:.
 Frog    69 LLFFQDKLSIEDFTAFAGVYGNKQ-DSAFPNLQSIVESSPSSLVLPSVDWYAANMLPTYLKERLG 132

  Fly   107 AKREHNSIDASGKL------TTPAKC------------------------AVG------------ 129
            ....|  :|.|..:      |.|:..                        |:|
 Frog   133 VSPLH--VDQSTLMELKLNETVPSLLVVRLPYGSSSGLLAAKDVLRANDQAIGQVLSTLKSEGVP 195

  Fly   130 -TALFVTFEDAAESREASLESHDAAIAAISKQFECKVAYLYLAAPSTA-PVVQRRTRRDTAATTG 192
             |||......:...:||||     |:..:.:|.      |..|.|:.: |.|...:.|:|..
 Frog   196 YTALLTALRPSRVIKEASL-----AVGNLGRQL------LATAQPTPSYPPVAFNSSRNTPC--- 246

  Fly   193 GIMWKSTN------QFQIFYTALLYNGNPITVTDLKLTNSSSTKLSVVMDTSVADKPITFDVVYN 251
             |::.:||      ..|:..|...:..:.:.:|. .|.|..::.|::....:|...|:|.....|
 Frog   247 -ILFWATNVSVTVDDVQVDLTDQTFTASNLDLTG-SLCNDINSVLAITYKEAVKGNPLTLRFFLN 309

  Fly   252 GGYFSLS----------NLVYDNN--NFRSSGVNAPTTFSYSCGNL----TLESAAVNNMYNTLS 300
            ..::.:|          .::|..|  .|.:..||||:.:|:.|..:    |..|..|:|......
 Frog   310 RRFYPVSARFWFTLSQVEIIYSGNTATFLAPQVNAPSNYSFHCQYISSWPTFGSVLVSNTSKNSP 374

  Fly   301 FKSLQLQ-APF--DGTYKEDFPFGDSWDCVGFVTPGILMGLFVVALLLVIMFVGVCWMMDINTMD 362
            ....||. |.|  .|.......|..:.||.||.:|||.|||....|.:.|:..|:..:|.:.|||
 Frog   375 ASKWQLHIAEFQIQGFNVTGMAFSYASDCAGFFSPGIWMGLITTLLFVFILTYGLHMVMSLKTMD 439

  Fly   363 RFDDPKGKTITI 374
            |||||||.:|.:
 Frog   440 RFDDPKGPSIAV 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VhaAC45	NP_610470.1	Lamp	211..309	CDD:480752	24/114 (21%)
		Ac45-VOA1_TM	328..366	CDD:466669	17/37 (46%)
atp6ap1.2	NP_001123842.1	VAS1_LD	244..390	CDD:461752	32/150 (21%)
		Ac45-VOA1_TM	405..443	CDD:466669	17/37 (46%)