Protein Alignment unpg and NKX3-1

DIOPT Version :10

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_006158.2
• Gene: NKX3-1 / 4824
• HGNCID: 7838
• Length: 234
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 71/252 - (28%)
• Similarity: 90/252 - (35%)
• Gaps: 82/252 - (32%)

  Fly   132 PPPHPPTHALEKQLPPTLPHPLDTRFLPFNPAAAGVAPTDLSYRRLAELMNQDYVHSLSVHARLQ 196
            |.|.|.....|...|||...|| |.||                                    :|
Human     5 PEPRPGEAKAEGAAPPTPSKPL-TSFL------------------------------------IQ 32

  Fly   197 HMAAAGRMHEDQANPGMAQLQEPTPPQAHSSPAKSGSHSPMEPALDVGMDEDFECSGDSCSDISL 261
            .:...|.    |...|....|....|:....|...|..|      ..|...|           .|
Human    33 DILRDGA----QRQGGRTSSQRQRDPEPEPEPEPEGGRS------RAGAQND-----------QL 76

  Fly   262 TMSPR------NYNGEMDKSRN-GAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNSKS 319
            :..||      ....|.:..|: |:|. .|||:.|   ||..|..             .:.....
Human    77 STGPRAAPEEAETLAETEPERHLGSYL-LDSENTS---GALPRLP-------------QTPKQPQ 124

  Fly   320 RRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKR 376
            :|.|.||:..|::||||:|..:||||..||:.:|.:|||:|.||||||||||.|.||
Human   125 KRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKR 181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	30/51 (59%)
NKX3-1	NP_006158.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..131		39/200 (20%)
		Homeodomain	125..181	CDD:459649	32/55 (58%)