Protein Alignment unpg and BARHL2

DIOPT Version :10

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_064447.1
• Gene: BARHL2 / 343472
• HGNCID: 954
• Length: 387
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 111/473 - (23%)
• Similarity: 160/473 - (33%)
• Gaps: 140/473 - (29%)

  Fly     7 LQNGEIGTM-ESPTTRLASKPFPKPFSIESLIANQTPATATPPSPPEERDQEQEAEQEQELSARA 70
            :.||:...: |:.|....|:..|.|.|       :.....|.||.|
Human    27 MMNGDFRPLGEARTADFRSQATPSPCS-------EIDTVGTAPSSP------------------- 65

  Fly    71 MVASSALGLTQFPLYNPWLHGYFAQNHERLTHLIAGGCYLPSSPAGHPA-AQQPQAQAQ----PQ 130
                  :.:|..| ..|.|.....|:|..|.|     ...|..||..|. :.||..|.|    ||
Human    66 ------ISVTMEP-PEPHLVADATQHHHHLHH-----SQQPPPPAAAPTQSLQPLPQQQQPLPPQ 118

  Fly   131 PPPPHPPTHALEKQLPPTLPHPLDTRFLPFNPAAAGVAPTDLSYRRLAELMNQDYVHSLSVHARL 195
            .|||.||     :||                .:||....|..|...:.:::...
Human   119 QPPPPPP-----QQL----------------GSAASAPRTSTSSFLIKDILGDS----------- 151

  Fly   196 QHMAAAGRMHEDQANPGMAQLQEPTPPQAHSSPAKSGS--HSPMEPALDVGMDEDFECSGDSCSD 258
            :.:||........::|             |.:|.:..:  |....|.|:   .||
Human   152 KPLAACAPYSTSVSSP-------------HHTPKQESNAVHESFRPKLE---QED---------- 190

  Fly   259 ISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNSKSRRRR 323
             |.|...:..:.:.|...:|.....|.|..|..|....|.:                  |.|:.|
Human   191 -SKTKLDKREDSQSDIKCHGTKEEGDREITSSRESPPVRAK------------------KPRKAR 236

  Fly   324 TAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVKA-GLTSHGLG 387
            |||:..||.:|||.|..:||||:.:|..:|.:|.|::.|||.|:||||.||||..| ||..  |.
Human   237 TAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLEL--LA 299

  Fly   388 RNGTTSGTKIVVPIPVHVNRFAVRSQHQQLEKMCLS-----------GPKPDLRKKLSAEA-IGG 440
            ..|..|..:.:.|.|...:...:.|..........:           .|.|.|::.|.... |.|
Human   300 EAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHG 364

  Fly   441 FEKFSGSTNASSPSGGPV 458
            ..  .|...|.:|...|:
Human   365 LG--PGGQPALNPLSSPI 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	27/51 (53%)
BARHL2	NP_064447.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..145		41/176 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	157..240		22/127 (17%)
		Homeodomain	233..289	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	367..387		4/14 (29%)