Protein Alignment unpg and Tlx3

DIOPT Version :10

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_036012630.1
• Gene: Tlx3 / 27140
• MGIID: 1351209
• Length: 338
• Species: Mus musculus
• Alignment Length: 366
• Identity: 81/366 - (22%)
• Similarity: 122/366 - (33%)
• Gaps: 128/366 - (34%)

  Fly   111 PSSP----AGHPAAQQPQAQAQPQPPPPHPPTHALEKQLPPTLPHPLDTRFLPFNPAAAGVAPTD 171
            |.:|    .|.||| .|.:.|||..||      .:|.......||       |..|.:.|:
Mouse    21 PGAPWPRRNGDPAA-SPPSPAQPFRPP------RMEAPASAQTPH-------PHEPISFGI---- 67

  Fly   172 LSYRRLAELMNQDYVHSLSVHARLQHMAAAGRMHEDQANPGMAQLQEPTPPQAHS---SP--AKS 231
                  .:::|                           :|.......|..|...|   .|  .:.
Mouse    68 ------DQILN---------------------------SPDQDSAPAPRGPDGASYLGGPPGGRP 99

  Fly   232 GSHSPMEPALDVGMDEDFECSGDSCSDISLTMSP---------RNYNGEMDKSRNGAYTNSDSED 287
            |:..|..||...|:...||.:|.  ..::|:::|         |...|.:......|.....|..
Mouse   100 GAAYPSLPASFAGLGAPFEDAGS--YSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVP 162

  Fly   288 CSDDEGAQSRHEGGGMGGKDSQGNGSS------------------------------SNSKSRRR 322
            ..           ..:||.:.....||                              :..|.::.
Mouse   163 TV-----------SSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKP 216

  Fly   323 RTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVKAGLTSHGLG 387
            ||:|:..|:.|||:.||.:|||:..||:.:|.|||:::.|||.||||||.||:|..|.      .
Mouse   217 RTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAE------E 275

  Fly   388 RNGTTSGTKIVVPIPVHVNRFAVRSQHQQLEKMCLSGPKPD 428
            |.....          ..:|..::.||...:|......:||
Mouse   276 REAERQ----------QASRLMLQLQHDAFQKSLNDSIQPD 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	28/51 (55%)
Tlx3	XP_036012630.1	PRK07764	<20..>109	CDD:236090	27/138 (20%)
		Homeodomain	214..270	CDD:459649	29/55 (53%)