Protein Alignment unpg and VAX2

DIOPT Version :10

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_036608.1
• Gene: VAX2 / 25806
• HGNCID: 12661
• Length: 290
• Species: Homo sapiens
• Alignment Length: 240
• Identity: 63/240 - (26%)
• Similarity: 96/240 - (40%)
• Gaps: 57/240 - (23%)

  Fly   253 GDSCSDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSN- 316
            |..|.|       |:..|:: ::..|.::.::....|....|.||..|....|:...|......
Human    22 GGRCGD-------RSGAGDL-RADGGGHSPTEVAGTSASSPAGSRESGADSDGQPGPGEADHCRR 78

  Fly   317 ---------------------SKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSE 360
                                 .:.:|.||:||:|||..||.||...:|:...||:::|..|.|||
Human    79 ILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSE 143

  Fly   361 VQVKIWFQNRRAKWKRVKAGLTSHGLGRNGTTSGTKIVVPIPVHVNRFAVRSQHQQLEK-MCLSG 424
            .|||:||||||.|.|:.:    |..|.:..::|.::          .||..:..:.||: ..||.
Human   144 TQVKVWFQNRRTKQKKDQ----SRDLEKRASSSASE----------AFATSNILRLLEQGRLLSV 194

  Fly   425 PK-----------PDLRKKLSAEAIGGFEKFSGSTN-ASSPSGGP 457
            |:           |.|.......::|.....|...| .||.|..|
Human   195 PRAPSLLALTPSLPGLPASHRGTSLGDPRNSSPRLNPLSSASASP 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	28/51 (55%)
VAX2	NP_036608.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..75		13/60 (22%)
		Homeodomain	103..159	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	205..240		9/35 (26%)