Protein Alignment unpg and DLX1

DIOPT Version :10

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_835221.2
• Gene: DLX1 / 1745
• HGNCID: 2914
• Length: 255
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 66/285 - (23%)
• Similarity: 104/285 - (36%)
• Gaps: 106/285 - (37%)

  Fly   145 LPPTLPHPLDTR--FLPFNPAAAGVAPTDLSY-----------------------RRLAELMNQD 184
            :|.:|..|:..:  |:.|.|....::|:.:|:                       ...:..:...
Human     6 MPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSASSFSRPLGYP 70

  Fly   185 YVHSLSVHARLQHMAAAGRMHEDQANPGMAQLQEPTPPQAHSSPAKSGSHSPMEPALDVGMDEDF 249
            ||:|:|.||...::::.      |:.||.|.|            |:|....|
Human    71 YVNSVSSHASSPYISSV------QSYPGSASL------------AQSRLEDP------------- 104

  Fly   250 ECSGDSCSDISLTMSPRNYNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSS 314
                                            .:|||..:..||.:.|..|.|
Human   105 --------------------------------GADSEKSTVVEGGEVRFNGKG------------ 125

  Fly   315 SNSKSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVK- 378
              .|.|:.||.::|.||..|.|.|...:||:|.||:::|.||.|::.||||||||:|:|:|::.
Human   126 --KKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMK 188

  Fly   379 ---AGLTSHGLGRNGTTSGTKIVVP 400
               |.|....|......|.....||
Human   189 QGGAALEGSALANGRALSAGSPPVP 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	26/51 (51%)
DLX1	NP_835221.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		8/31 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..118		9/79 (11%)
		Homeodomain	129..185	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..230		3/10 (30%)