Protein Alignment unpg and DBX1

DIOPT Version :10

• Sequence 1: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001025036.2
• Gene: DBX1 / 120237
• HGNCID: 33185
• Length: 343
• Species: Homo sapiens
• Alignment Length: 385
• Identity: 86/385 - (22%)
• Similarity: 124/385 - (32%)
• Gaps: 147/385 - (38%)

  Fly   110 LPSSPAGHPAAQQPQAQAQPQPPPPHPPTHALEKQL--------------------PPT-LPHPL 153
            |.:.|||:|:..:|            .||..|.:.|                    ||. ||..:
Human     6 LLAPPAGYPSLLRP------------TPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSV 58

  Fly   154 DTRFLPFNPAAAGVAPTDLSYRRLAELMNQDYVHSLSVHARLQHMAAAGRMHEDQANPGMAQLQE 218
            .|..:  :|...| |||.|:....::|                            .:||....:.
Human    59 PTASM--SPPRQG-APTALTDTGASDL----------------------------GSPGPGSRRG 92

  Fly   219 PTPPQAHSSPA--------------KSGSHSPMEPALDVGMDEDFECSGDSCSDISLTMSPRN-- 267
            .:||.|. |||              .||..:...|||                  ..::.|:.
Human    93 GSPPTAF-SPASETTFLKFGVNAILSSGPRTETSPAL------------------LQSVPPKTFA 138

  Fly   268 ---YNGEMDKSRNGAYTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGS---SSNSKSRR---RR 323
               :.|........:|..:.|...                  ...|..|   ::..|.||   ||
Human   139 FPYFEGSFQPFIRSSYFPASSSVV------------------PIPGTFSWPLAARGKPRRGMLRR 185

  Fly   324 TAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVKAG--LTSHG- 385
            ..|:..|...||:.|..:||:|..:|.::|..|.|.:.||||||||||.||:..|..  |:|.|
Human   186 AVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGC 250

  Fly   386 -----------------LGRNGTTSGTKIVVP-IPVHVNRFAVRSQHQQLEKMCLSGPKP 427
                             :|:.|..:..:...| .|.|...:...|..|.|....|.||.|
Human   251 REQTLPTKLNPHPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSDPQHLRDPRLPGPLP 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	24/51 (47%)
DBX1	NP_001025036.2	PRK12323	<49..182	CDD:481241	34/200 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	56..100		13/75 (17%)
		Homeodomain	184..238	CDD:459649	26/53 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..343		16/71 (23%)