Protein Alignment CG8008 and Slc46a1

DIOPT Version :10

• Sequence 1: NP_001137623.1
• Gene: CG8008 / 35935
• FlyBaseID: FBgn0033387
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001013991.1
• Gene: Slc46a1 / 303333
• RGDID: 1309472
• Length: 459
• Species: Rattus norvegicus
• Alignment Length: 537
• Identity: 111/537 - (20%)
• Similarity: 206/537 - (38%)
• Gaps: 135/537 - (25%)

  Fly    28 IEPVVFMLLFSHTLSGTIQRNQVIYQTCTVIFHYNESDCKQLDVKNASAE--INAIETELQPYVA 90
            :||:||:..|:..|.|.: ..|.|:...:....||.:..:: :..|.||:  :..:||....:
  Rat    25 VEPLVFLANFALVLQGPL-TTQYIWHRISTELGYNGTRHRE-NCGNQSADPVLKEVETLTSHW-- 85

  Fly    91 NLFLARTLLESIVPAFCGLF----IGSWSDHYGRKPLLIVSMIGFSASFLMMAAICELSSYYVV- 150
                  ||..::.....|||    :|:|||..||:|||:::.:|     |::.|:.   |.:||
  Rat    86 ------TLYMNVGGFLVGLFWSTLLGAWSDRVGRRPLLVLASLG-----LLLQAVV---SIFVVQ 136

  Fly   151 ---NPWWYIMAAVPHSLLGGNCVFSVAAFCFISDITDCKSRPYRMIFMESLFFIGLTSGSLLSSF 212
               :..::::.....:|||.......|:|..::|::...||.:||..:|:...:..|..|||...
  Rat   137 LQLHIGFFVLGRALCALLGDFNGLLAASFASVADVSSNHSRTFRMALLEACIGVAGTLASLLGGH 201

  Fly   213 VYAAVGSAATIGISGCIVTFATLFIIFFVPESLHFHKEQETKNAITANVEKECIDSKVPITACDL 277
            ...|.|.|....::..::...||:..|...|::
  Rat   202 WLRAQGYANPFWLALAVLIVMTLYAAFCFGETV-------------------------------- 234

  Fly   278 QLDRVAIDCPPNFMNDEEPGKDKRMELPTPATPAMSFDDDLLAKYVERLPQKAEERKRQEAEEQA 342
                            :||
  Rat   235 ----------------KEP---------------------------------------------- 237

  Fly   343 KKAGLFSMVHIRDMISTCFKRRDHHARAIIWLVTLAMFLSIFVFDGVMTVMYLF-VREKFHWTVR 406
            |...||::.|.|.::..........:|..:.|.:||:|:.:.|..|...::.|: :.....|..:
  Rat   238 KSTRLFTLRHHRSIVQLYVVPAPEKSRMHLALYSLAIFVVVTVHFGAQDILTLYELSTPLCWDSK 302

  Fly   407 DYTFFETVSHLVPMIGALIGFLILRKVFRLSVVTLALLAFFSEILNNLAKGFATMPWHMYLSVTL 471
            ...:.....|| |.:.:|:|..:|:  |.|:...:|.:.....||..:...|||:...|:....|
  Rat   303 LIGYGSAAQHL-PYLTSLLGLRLLQ--FCLADTWVAEIGLAFNILGMVVFAFATITPLMFTGYGL 364

  Fly   472 GVFRSISGPMCRTIVSNIVPPSDLGKIFSIKNVLQSFAPFVAAPLYTLIYKRSLTTYPGLFNFVS 536
            .....::.|:.|..:|.:|..|:.|.:||....:.|.|..:|:.::.       :.||...||:.
  Rat   365 LFLSLVTTPVIRAKLSKLVSESEQGALFSAVACVNSLAMLMASGIFN-------SLYPATLNFMK 422

  Fly   537 SFLYLL--SFVFIGYVL 551
            .|.:||  ..:||..:|
  Rat   423 GFPFLLGAGLLFIPAIL 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8008	NP_001137623.1	MFS_SLC46	25..551	CDD:340944	110/535 (21%)
Slc46a1	NP_001013991.1	MFS	22..444	CDD:475125	111/537 (21%)