Protein Alignment Mys45A and SDA1

DIOPT Version :10

• Sequence 1: NP_610455.1
• Gene: Mys45A / 35925
• FlyBaseID: FBgn0033379
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_011761.3
• Gene: SDA1 / 853160
• SGDID: S000003477
• Length: 767
• Species: Saccharomyces cerevisiae
• Alignment Length: 783
• Identity: 267/783 - (34%)
• Similarity: 406/783 - (51%)
• Gaps: 109/783 - (13%)

  Fly     9 LPENLPQLQNLIKRDPESYSDEFHIQYQHFLSLLEVFALN------------------------- 48
            ||.|:..||||:|||||||.:||..||.|:.||.::|.||
Yeast    10 LPTNIILLQNLVKRDPESYQEEFLQQYAHYESLRDIFMLNGLAGGDSAAATNGLDVGNGSSTMAG 74

  Fly    49 -----PSEENKSLDDIVMFVAQVAQCYPAVCEEFPKRLSDLLKNYATVLDPAMRNCFVKALILLR 108
                 .|.....|.::|.||:||..|:|.....||..|..||..:...|...::...:..|.:||
Yeast    75 TNGTTMSTSTSQLIELVGFVSQVCSCFPRETANFPSELKQLLLEHHKSLPFELKEKILSCLTMLR 139

  Fly   109 NKNLVPALDILELFFQLL------------RCPDKNLRTFLQTHIVTDIKNMNAKHKDMKLNSSL 161
            ||:::.|.::::..|.||            ....|.||..:.|::::.:|:.|...|:.|||.|.
Yeast   140 NKDVITAEELIQSLFPLLVAYSSHGNSLGVNSHAKELRKIIYTNLISLLKSCNTNGKNQKLNKST 204

  Fly   162 QAFMYSMLKDANPK---AAKMSADIMIELYKKNIWNDSKTVNVIATVGCFSKVTKVLVTSLKFFL 223
            ||..:::|...:.:   |.|::.    ||:::.||:||:||.:: |.....:..|::::.:.|||
Yeast   205 QAVCFNLLDQPDSQGIWATKLTR----ELWRRGIWDDSRTVEIM-TQAALHQDVKIVMSGVMFFL 264

  Fly   224 GHD---EEDEEEDTDSENEVDLKGALMANRVNKKTKKRTKQLAQIKKQAVK-AQKKKKNAPA--- 281
            ..|   ||:.||:::.|:..||.......:|||||.:|.|:|    :.|:| .:|||||.|.
Yeast   265 DADREREENFEENSEDEDGFDLDALRHKMQVNKKTGRRGKKL----ENAIKTVKKKKKNGPGAPQ 325

  Fly   282 --FNFSGIHLVHNPQGMAEGLFKQLQA--TNERF--EVKLMHLDVISRLIGIHDLFLFGFYPYIT 340
              .|||.|||:.:|||.||.|||:..:  |..:|  |.|:..:.::|||||.|.|.:.|.|.:..
Yeast   326 GYLNFSAIHLLRDPQGFAEKLFKEHLSGKTKNKFDMEQKISLMQLLSRLIGTHKLIVLGIYTFFL 390

  Fly   341 RFLQPHQRQVTRVLQFAAQASHELVPGDIIEPILKTIANNFITERNSSDVMAIGLNATREICMRC 405
            ::|.|.||.|||::...|||.|:|||.::|..:::.||:.|:::..:::|.|.|:|..||||.|.
Yeast   391 KYLTPKQRDVTRIMSACAQACHDLVPPEVINVMVRKIADEFVSDGVANEVAAAGINTIREICSRA 455

  Fly   406 PLAMGEDLLQDLAMYKTYKEKSVMMAARSLITLYREQLPALLHKKDRGRQTEAQAER-------- 462
            |||:.|.|||||..||..|.|.|.|||:|||.|||:..|.:|.|||||:....:.:.
Yeast   456 PLAIDEILLQDLVEYKGSKAKGVNMAAKSLIALYRDVAPEMLKKKDRGKNAAMEVQEAKKGGKDS 520

  Fly   463 KVRAYGEREVHDTVLGAEALLKDSKTIDIESE-DDTDSN------------DGEWVNVAHSDGEG 514
            |...:|.......:.|.|.|.|..|....||| :|.|:|            |||||.:
Yeast   521 KRPQFGADNSVQGIAGIELLAKWKKEHGEESENEDADANWEVDVDSEEDDVDGEWVTM------- 578

  Fly   515 GGADDDEEDEDEDEDDDDEDEDEENSNDEENEDEDNSDEGVESGEESAKAKKEKKDMRILNQKEA 579
                    |.|::.|.|.||.|:|..|.:..|.:.:.:...:..|:..|.::|..|   ::.:.|
Yeast   579 --------DSDKEYDVDMEDSDDEKDNAKGKESDSDLELSDDDDEKEVKDEQEDAD---IDPEAA 632

  Fly   580 AQELALTRIFTDEDFKRINAANLKKTVTSARKRPLEQDRAEFVKLNSIEMIYKKRKHDKESRLET 644
            .:|:|.|||.|..||.::.....:::|........:..|.|.|..:::.... |.|..:|.||:.
Yeast   633 FREIASTRILTPADFAKLQELRNEESVAKIMGIHKQDKREELVDASTLTGPI-KYKQSREERLQK 696

  Fly   645 VQAGRQDRERFGWKDGRVNEHCSKTNREKRKTKNFGMLRHK--ARSKVKKSFKDKQQALRKHLLH 707
            |..||:.|::||.:.|:.:...|.|||||.:.|||.|..||  .|.|.|.|.:|||:.||.|:..
Yeast   697 VLEGREGRDKFGSRRGKRDNMRSTTNREKERRKNFVMSIHKRSVRGKQKMSLRDKQKVLRAHITK 761

  Fly   708 QKK 710
            |||
Yeast   762 QKK 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mys45A	NP_610455.1	NUC130_3NT	62..111	CDD:462384	16/48 (33%)
		SDA1	409..711	CDD:461611	109/325 (34%)
SDA1	NP_011761.3	NUC130_3NT	93..142	CDD:462384	16/48 (33%)
		SDA1	459..765	CDD:461611	109/325 (34%)