Protein Alignment Mys45A and Sdad1

DIOPT Version :8

• Sequence 1: NP_610455.1
• Gene: Mys45A / 35925
• FlyBaseID: FBgn0033379
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_001006959.1
• Gene: Sdad1 / 289504
• RGDID: 1359112
• Length: 686
• Species: Rattus norvegicus
• Alignment Length: 721
• Identity: 362/722 (50%)
• Similarity: 488/722 (68%)
• Gaps: 57/722 (8%)

  Fly     5 NNNQLPENLPQLQNLIKRDPESYSDEFHIQYQHFLSLLEVFALNPSEENKSLDDIVMFVAQVAQC 69
            |||:||.|||||||||||||.:|.:||..||.|:.|.:|:|.|.|::.:|.|.::|||:||:..|
  Rat     5 NNNKLPSNLPQLQNLIKRDPPAYVEEFLQQYNHYKSNMEIFKLQPNKPSKELAELVMFMAQIGHC 69

  Fly    70 YPAVCEEFPKRLSDLLKNYATVLDPAMRNCFVKALILLRNKNLVPALDILELFFQLLRCPDKNLR 134
            ||....|||:.|.|||....|||||.:|..|.|||||||||||:...|:|||||:||||.||.||
  Rat    70 YPEHLSEFPQELKDLLSYNHTVLDPDLRMTFCKALILLRNKNLINPSDLLELFFELLRCRDKLLR 134

  Fly   135 TFLQTHIVTDIKNMNAKHKDMKLNSSLQAFMYSMLKDANPKAAKMSADIMIELYKKNIWNDSKTV 199
            ..|.|||||||||:|||||:.|:|..||.|||:||:|:|..|||||.|:|||||::|||||:|||
  Rat   135 KTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTV 199

  Fly   200 NVIATVGCFSKVTKVLVTSLKFFLGHDEEDEEEDTDSENEVD---LKGALMANRVNKKTKKRTKQ 261
            ||| |..||||:||:||.:|.||||.||| |::|:|||:|.|   .:..|:.....||..|..|:
  Rat   200 NVI-TTACFSKITKILVAALTFFLGKDEE-EKQDSDSESEDDGPTARDLLVQYATGKKGSKNKKK 262

  Fly   262 LAQIKKQAVKAQKKKKNAPAFNFSGIHLVHNPQGMAEGLFKQLQATNERFEVKLMHLDVISRLIG 326
            |.:..| .:|.|||||....||||.|||:|:||..||.|.|||::..||||||:|.:::||||:|
  Rat   263 LEKAMK-VLKKQKKKKKPEVFNFSAIHLIHDPQDFAEKLLKQLESCKERFEVKMMLMNLISRLVG 326

  Fly   327 IHDLFLFGFYPYITRFLQPHQRQVTRVLQFAAQASHELVPGDIIEPILKTIANNFITERNSSDVM 391
            ||:||||.|||::.||||||||:||::|.|||||||.|||.:||:.:|.|:||||:|::||.:||
  Rat   327 IHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLLTVANNFVTDKNSGEVM 391

  Fly   392 AIGLNATREICMRCPLAMGEDLLQDLAMYKTYKEKSVMMAARSLITLYREQLPALLHKKDRGRQT 456
            .:|:||.:||..||||||.|:||||||.|||:|:|:|||:||:||.|:|...|.:|.||.||:.|
  Rat   392 TVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPT 456

  Fly   457 EAQAERKVRAYGEREVHDTVLGAEALLKDSKTIDIESEDDTDSNDGEWVNVAHSDGEGGGADDDE 521
            ||..|.:::.|||.:..|.:.|||.|       ::|.|::|::::..|.:.:.|
  Rat   457 EASIEARIQEYGELDAKDYIPGAEVL-------ELEKEENTENDEDGWESASLS----------- 503

  Fly   522 EDEDEDEDDDDEDEDEENSNDEENEDEDNSDEGVESGEESAKAKKEKKDMRILNQKEAAQELALT 586
                 :|::|.|..|..:|:||               |:.|.||| ...|.:..:|..|..::.:
  Rat   504 -----EEEEDGEWVDVHHSSDE---------------EQQAVAKK-LDSMPMEERKAKAAAVSTS 547

  Fly   587 RIFTDEDFKRINAANLKKTVTS----ARKRPL------EQDRAEFVKLNSIEMIYKKRKHDKESR 641
            |:.|.:||::|..|.:||.:.:    |:||..      |:.|.|.:.|..||.::||.|.|||:|
  Rat   548 RVLTQDDFQKIRMAQMKKEMDAAPGKAQKRKYLDMDSDEESRGELLSLRDIERLHKKPKSDKETR 612

  Fly   642 LETVQAGRQDRERFGWKDGRVNEHCSKTNREKRKTKNFGMLRH--KARSKVKKSFKDKQQALRKH 704
            |.|..|||.||:.|..|..::|...|.||:||:|.|||.|:|:  ..|||..:||::||.|||..
  Rat   613 LATAMAGRTDRKEFVRKKTKINPFSSSTNKEKKKQKNFMMMRYSQNVRSKTSRSFREKQLALRDA 677

  Fly   705 LLHQKK 710
            ||.::|
  Rat   678 LLKKRK 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mys45A	NP_610455.1	NUC130_3NT	62..111	CDD:285384	29/49 (59%)
		SDA1	409..711	CDD:283052	118/315 (37%)
Sdad1	NP_001006959.1	NUC130_3NT	62..111	CDD:285384	29/49 (59%)
		SDA1	409..683	CDD:283052	117/313 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C150648533
eggNOG	1	0.900				E1_KOG2229
Hieranoid	1	1.000
Homologene	1	1.000				H6036
Inparanoid	1	1.050	666	1.000	Inparanoid score	I700
OMA	1	1.010
OrthoDB	1	1.010				D270594at33208
OrthoFinder	1	1.000				FOG0003939
OrthoInspector	1	1.000				T1086732
orthoMCL	1	0.900				OOG5_128086
Panther	1	1.100			LDO	PTHR12730
Phylome	1	0.910		0.667	Consistency score
TreeFam	1	0.960
	13	12.770