Protein Alignment Mys45A and sda1

DIOPT Version :8

• Sequence 1: NP_610455.1
• Gene: Mys45A / 35925
• FlyBaseID: FBgn0033379
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_595163.1
• Gene: sda1 / 2539889
• PomBaseID: SPBC106.14c
• Length: 719
• Species: Schizosaccharomyces pombe
• Alignment Length: 747
• Identity: 258/748 (34%)
• Similarity: 406/748 (54%)
• Gaps: 85/748 (11%)

  Fly     9 LPENLPQLQNLIKRDPESYSDEFHIQYQHFLSLLEVFALNPSEENKSLDDIVMFVAQVAQCYPAV 73
            ||.|||.||:|:|:||:||.:||..|:.|:.:..|:|.:|||.:......::.|::|....|..|
pombe    10 LPNNLPHLQHLVKKDPKSYREEFLQQWNHYETAREIFLVNPSSDISEFCSLIDFISQTCNYYHDV 74

  Fly    74 CEEFPKRLSDLLKNYATVLDPAMRNCFVKALILLRNKNLVPALDILELFFQLLR-CPDKNLRTFL 137
            ..:||..|.:||:...|:....:....|..|:||:||.::..:.:|:.||.|.| .|.:.:|..|
pombe    75 TADFPSELIELLQKNHTIFPFELCEKIVLCLVLLKNKTVISPITLLQCFFPLFRENPTRGVRELL 139

  Fly   138 QTHIVTDIKNMNAKHKDMKLNSSLQAFMYSMLKDANP---------------KAAKMS----ADI 183
            ...:...|:|.|.:.|:.|||.::|:.:::::..:..               .|:::|    ..:
pombe   140 YQQVSLTIRNANKQAKNDKLNKAVQSALFTLVDGSGSGSATHTDYSGQKREYSASELSGVWAVKM 204

  Fly   184 MIELYKKNIWN-DSKTVNVIATVGCFSKVTKVLVTSLKFFLGHDEEDEEEDTDSENEVDLKGALM 247
            :.:|:|:|:|: |::.||::.: ...|...||::..:.||||.|.::|||::|.|.. |:...|.
pombe   205 VRDLWKRNVWSGDARAVNIMKS-AALSSNPKVMLAGIYFFLGADNQEEEEESDDEGP-DVSKLLH 267

  Fly   248 ANRVNKKTKKRTKQLAQIKKQAVKAQKKKKNAPA-FNFSGIHLVHNPQGMAEGLF-KQLQATNER 310
            ...||||||.|...|.:.:....|.::.|:|.|. .||..:.|:|:|||.||.|| |.|.::..|
pombe   268 QANVNKKTKSREAALLRARAVVKKKERGKQNVPTNVNFPALQLLHDPQGFAEELFEKHLASSKSR 332

  Fly   311 FEV--KLMHLDVISRLIGIHDLFLFGFYPYITRFLQPHQRQVTRVLQFAAQASHELVPGDIIEPI 373
            ..:  ||:.|.:::||:|.|.|.:.|.|.::.::|.||||.||:.|...||||||.||.|.:||:
pombe   333 LSMDQKLVVLRLLTRLVGSHKLTVLGLYSFLMKYLTPHQRDVTQFLACLAQASHEFVPPDALEPL 397

  Fly   374 LKTIANNFITERNSSDVMAIGLNATREICMRCPLAMGEDLLQDLAMYKTYKEKSVMMAARSLITL 438
            ::.||:.|:|...:::|:..|:||.||:|.|.||||..||||||..||:.|:|.||||:||||||
pombe   398 VRKIADEFVTSGVANEVVCAGINAIREVCARAPLAMTPDLLQDLTEYKSSKDKGVMMASRSLITL 462

  Fly   439 YREQLPALLHKKDRGRQTEAQAERKVRAYGEREVHDTVLGAEALLKDSKTIDIESEDDTDSNDGE 503
            |||..|.:|.:||||                                 |...||.:|.|....||
pombe   463 YREVAPDMLKRKDRG---------------------------------KLASIEMKDRTPLKYGE 494

  Fly   504 WVNVAHSDGEGG-------GADDDEEDEDEDEDDDDE-DEDEENSNDEENEDEDNSDEGVE---- 556
            .:||.|  |..|       .|:..||.|:.|:.|:.| .||.:||:|.....:.:||:.:|
pombe   495 ELNVTH--GIQGLELLAQYKAEHGEEGENGDDWDNWEVSEDGQNSDDSGGWIDVDSDDNIELSDS 557

  Fly   557 -SGEESAKAKKEKKDMRILNQKEAAQ---ELALTRIFTDEDFKRI----NAANLKKTVTSARKRP 613
             ..||.|.|:||..:....:|||...   |||...|.|..|.|::    ..|.:.:.|...::..
pombe   558 DEEEEKATARKESDEKGSSSQKELVDRMTELASQSILTPNDLKKLEELREQAGVDRLVNGPKRSL 622

  Fly   614 LEQDRAEFVKLNSIEMIYKKRKHDKESRLETVQAGRQDRERFGWKDGRVNEHCSKTNREKRKTKN 678
            ...|.|  |:.:.||...||.|:|:|:|:.:|..||:.|::|..|....|. .|.:|:.|::.||
pombe   623 KRPDDA--VEADEIEGPRKKAKNDREARIASVMEGREGRDKFSSKKAGFNP-TSLSNKRKQRNKN 684

  Fly   679 FGMLRHKARSKVKKSFKDKQQALRKHLLHQKK 710
            |.|::||.:.|..:|...||:.||:|:..:|:
pombe   685 FMMIKHKLKGKAGRSLVQKQKVLREHVAREKR 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mys45A	NP_610455.1	NUC130_3NT	62..111	CDD:285384	16/49 (33%)
		SDA1	409..711	CDD:283052	110/323 (34%)
sda1	NP_595163.1	NUC130_3NT	63..111	CDD:285384	15/48 (31%)
		SDA1	433..717	CDD:283052	110/323 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	402	1.000	Inparanoid score	I369
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0003939
OrthoInspector	1	1.000				T1124738
orthoMCL	1	0.900				OOG5_128086
Panther	1	1.100			LDO	PTHR12730
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1296
TreeFam	1	0.960
	10	9.960