Protein Alignment Mys45A and pro-3

DIOPT Version :10

• Sequence 1: NP_610455.1
• Gene: Mys45A / 35925
• FlyBaseID: FBgn0033379
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_001379304.1
• Gene: pro-3 / 180256
• WormBaseID: WBGene00012676
• Length: 801
• Species: Caenorhabditis elegans
• Alignment Length: 778
• Identity: 284/778 - (36%)
• Similarity: 430/778 - (55%)
• Gaps: 101/778 - (12%)

  Fly    12 NLPQLQNLIKRDPESYSDEFHIQYQHFLSLLEVFALNPS---EENKSLDDIVMFVAQVAQCYPAV 73
            ||..:|.:|::|||||.:||..|:.:|:..:::..|.|.   :|.:||.|.|:|::.:|:.||..
 Worm    46 NLGLMQEIIRKDPESYKEEFLEQFNYFVQTMKLLHLQPEQSRQEMQSLVDSVLFLSGLAKHYPKE 110

  Fly    74 CEEFPKRLSDLLKNYATVLDPAMRNCFVKALILLRNKNLVPALDILELFFQLLRCPDKNLRTFLQ 138
            .::|...|.:||:.....|||.:|..|.|||:||||::::..:.::|.||:|::..||.||.||.
 Worm   111 SKQFSDSLFELLREQGAGLDPEVRMAFCKALVLLRNQDMIDPIILMETFFELVKVEDKVLRKFLL 175

  Fly   139 THIVTDIKNMNAKHKDMKLNSSLQAFMYSMLKDANPKAAKMSADIMIELYKKNIWNDSKTVNVIA 203
            :.|...:|.:..|.||:|:...:|...:|.:||:....|:.:..:.|:.:::..|.|::|.||||
 Worm   176 SSISAHLKRVYHKKKDVKMLGKIQNLCFSKMKDSRSIVARAAQLVCIDAFRRKFWRDARTANVIA 240

  Fly   204 TVGCFSKVTKVLVTSLKFFLGHD------EEDEEEDTDSE-NEVDLKGALMANRVNKKTKKRTKQ 261
            . .||.||.|:.|||:|||||.:      |:.:|.|:|:| |...||..:.:.|..|||:||.|.
 Worm   241 Q-ACFHKVAKIQVTSMKFFLGSENENGDAEDSDEMDSDAEDNTKTLKEVMTSFRNVKKTRKREKN 304

  Fly   262 LAQIKKQAVKAQKKKK--NAPAFNFSGIHLVHNPQGMAEGLFKQLQATN-ERFEVKLMHLDVISR 323
            :.:.||...|.:|.||  .:...|...|..:::||...:.||..::|.. :.|||:|..:.:.:|
 Worm   305 VERAKKMISKKKKAKKEGRSKECNLMAIQSLYDPQEFVDRLFGAVEAKKMDNFEVRLFKIALCAR 369

  Fly   324 LIGIHDLFLFGFYPYITRFLQPHQRQVTRVLQFAAQASHELVPGDIIEPILKTIANNFITERNSS 388
            :||||.|....||.|:.|||||.||.||::|.:||||.||:||.|.:|.:::.|||||:|:|||.
 Worm   370 IIGIHRLHTLSFYSYLHRFLQPKQRDVTKILLYAAQACHEMVPPDTVEQLIRVIANNFVTDRNSP 434

  Fly   389 DVMAIGLNATREICMRCPLAMGEDLLQDLAMYKTYKEKSVMMAARSLITLYREQLPALLHKKDRG 453
            :.|.:|:||.|||...||.|..|:||:||:.|||||.|:|.|||||||||:|...|.||.:||||
 Worm   435 EAMTVGINAIREILSNCPFAATEELLRDLSEYKTYKNKNVSMAARSLITLFRAVNPKLLARKDRG 499

  Fly   454 RQTEAQAE-RKVRAYGEREVHDTVLGAEAL----------------------LKDSKTIDIESED 495
            :..|...| .:...:...:|||.:.|||.|                      :.|..|.|::::|
 Worm   500 KPQEKDDEDEEYNGFARPKVHDFISGAEILDEDAADGEQGHLEEDGTDSELDVSDVDTDDVDTDD 564

  Fly   496 DTD--------------SNDGEWVNVAHSDGEGGGADDDEEDEDEDEDDDDEDEDEENSNDEENE 546
            |.|              .||.|      ||.      ||||.|||:|.||:|:|.|.:..:||..
 Worm   565 DADEPVAKKKRVEQKSVENDAE------SDA------DDEEIEDEEEMDDEEEEIEISDEEEEEI 617

  Fly   547 DEDNSDEGVESGEESAKAKKEKKDMRILNQKEAAQELALTRIFTDEDFKRINAANLKKTVTS--- 608
            |::..:|.|...|.|...:|:        .|..|.:.::.||.|.||||.|.|..|||.:..
 Worm   618 DDEAEEEAVVEEEASEAVEKD--------PKLKASKNSMDRIMTQEDFKNIKAYQLKKQLIGEKR 674

  Fly   609 --------------------ARKRPLEQDRAEFVKLNSIEMIYKKRKHDKESRLETVQAGRQDRE 653
                                |.|..|::......:|:.||..|||::..||.|:..|.|||.|.:
 Worm   675 LKKQMGKGRSQADERIVDEMAEKLELKRSSDGLARLSDIEHFYKKKRQSKEERMADVMAGRADED 739

  Fly   654 RFGWKDGRVNE---HCSKTNREKRKTKNFGMLRHKARSKVK-KSFKDKQQALRKHLLHQKKMK 712
               :|.||..:   |..:||.:..|.|.|.|:::|.|.:.: :||:|:|::||.:|:.|...|
 Worm   740 ---YKFGRPKKNGAHVGRTNDQNSKKKVFAMVKNKIRGRNRQRSFRDQQKSLRHYLMRQSGRK 799

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mys45A	NP_610455.1	NUC130_3NT	62..111	CDD:462384	20/48 (42%)
		SDA1	409..711	CDD:461611	121/365 (33%)
pro-3	NP_001379304.1	NUC130_3NT	99..148	CDD:462384	20/48 (42%)
		SDA1	456..795	CDD:461611	120/361 (33%)