Protein Alignment spab and DKK2

DIOPT Version :10

• Sequence 1: NP_610434.1
• Gene: spab / 35901
• FlyBaseID: FBgn0033358
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_055236.1
• Gene: DKK2 / 27123
• HGNCID: 2892
• Length: 259
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 52/259 - (20%)
• Similarity: 75/259 - (28%)
• Gaps: 109/259 - (42%)

  Fly    22 PSLAASASSFASGNAWQRALFG--RESRNLMHRRAPFSGAADLGLDEYLGPYGAVEQEQHQPHPP 84
            |..||:.|:    ..:|...||  ::.:|| .:..|.|...:..:..|.          |.||.
Human    47 PGQAANRSA----GMYQGLAFGGSKKGKNL-GQAYPCSSDKECEVGRYC----------HSPHQ- 95

  Fly    85 PQQMRQQTEVYGIVEPLIEDTPC-----ADRPCLLNDDCCPSGVCVSTYGEGKCVYVF------- 137
                              ..:.|     ..:.|..:..||||..|    ..|.|:.|.
Human    96 ------------------GSSACMVCRRKKKRCHRDGMCCPSTRC----NNGICIPVTESILTPH 138

  Fly   138 ------GRQRDLCQGHADCPQGSSCMLVPQEGAWRCEPSVESGGSTSLLEGIFGAKERQPLGSEC 196
                  .|.||...||..          ..:..|:     ..|...:.:..|.|.:     |..|
Human   139 IPALDGTRHRDRNHGHYS----------NHDLGWQ-----NLGRPHTKMSHIKGHE-----GDPC 183

  Fly   197 SSSSDCQVINGMCC---------------------QQQRLHHRAAI--------KLSCGYFRDA 231
            ..||||  |.|.||                     |:::..|...|        .|||..::||
Human   184 LRSSDC--IEGFCCARHFWTKICKPVLHQGEVCTKQRKKGSHGLEIFQRCDCAKGLSCKVWKDA 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spab	NP_610434.1	None
DKK2	NP_055236.1	Dkk2_Cys1	74..128	CDD:438009	14/86 (16%)
		DKK-type Cys-1	78..127		13/81 (16%)
		Dkk2_Cys2	175..258	CDD:437999	20/78 (26%)
		DKK-type Cys-2	183..256		17/65 (26%)