Protein Alignment spab and DKK4

DIOPT Version :10

• Sequence 1: NP_610434.1
• Gene: spab / 35901
• FlyBaseID: FBgn0033358
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_055235.1
• Gene: DKK4 / 27121
• HGNCID: 2894
• Length: 224
• Species: Homo sapiens
• Alignment Length: 179
• Identity: 41/179 - (22%)
• Similarity: 62/179 - (34%)
• Gaps: 58/179 - (32%)

  Fly    62 LGLDEYLGPYGAVEQEQHQPHPPPQQMRQQTEVYGIVE--PLIEDTPCADRP-CLLNDD------ 117
            |||.....|.||:..:.:       .:|...:::|..:  ..:.||.|..|. ||...|
Human     7 LGLSWLCSPLGALVLDFN-------NIRSSADLHGARKGSQCLSDTDCNTRKFCLQPRDEKPFCA 64

  Fly   118 --------------CCPSGVCVSTYGEGKCVY------VFGRQRDLCQG-HADCPQGSSCMLVPQ 161
                          |||..:||:..    |..      :..||.|...| ||:...|...    |
Human    65 TCRGLRRRCQRDAMCCPGTLCVNDV----CTTMEDATPILERQLDEQDGTHAEGTTGHPV----Q 121

  Fly   162 EGAWRCEPSVESGGSTSLLEGIFGAKERQPLGSECSSSSDCQVINGMCC 210
            |...:.:||::...         |.|.::  |..|..:.||.  .|:||
Human   122 ENQPKRKPSIKKSQ---------GRKGQE--GESCLRTFDCG--PGLCC 157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spab	NP_610434.1	None
DKK4	NP_055235.1	Dkk4_Cys1	37..91	CDD:438007	12/57 (21%)
		DKK-type Cys-1	41..90		12/52 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	109..139		9/42 (21%)
		Dkk4_Cys2	128..221	CDD:438001	11/43 (26%)
		DKK-type Cys-2	145..218		6/15 (40%)