DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment spab and Dkk4

DIOPT Version :9

Sequence 1:	NP_610434.1	Gene:	spab / 35901	FlyBaseID:	FBgn0033358	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_663567.1	Gene:	Dkk4 / 234130	MGIID:	2385299	Length:	221	Species:	Mus musculus

Alignment Length:	174	Identity:	37/174 - (21%)
Similarity:	58/174 - (33%)	Gaps:	48/174 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 LGLDEYLGPYGAVEQEQHQPHPPPQQMRQQTEVYGIVEPLIEDTPCADRPCLLNDDCCPSGVCVS 126
            |||..:..|..|:..:.:       .::...:|.|..:..:         |..:.||.....|::
Mouse     7 LGLSWFCSPLAALVLDFN-------NIKSSADVQGAGKGSL---------CASDRDCSEGKFCLA 55

  Fly   127 TYGEGKCVYVFGRQRDLCQGHADCPQGSSCM-----------------LVPQEGA-------WRC 167
            .:.|........|.|..||..|.|..|:.|:                 ...|:||       |..
Mouse    56 FHDERSFCATCRRVRRRCQRSAVCCPGTVCVNDVCTAVEDTRPVMDRNTDGQDGAYAEGTTKWPA 120

  Fly   168 EPSVESG-GSTSLLEGIFGAKERQPLGSECSSSSDCQVINGMCC 210
            |.:...| .||...:...|.:     |..|..:|||.  .|:||
Mouse   121 EENRPQGKPSTKKSQSSKGQE-----GESCLRTSDCG--PGLCC 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spab	NP_610434.1	None
Dkk4	NP_663567.1	Dickkopf_N	41..91	CDD:368068	13/49 (27%)
		DKK-type Cys-1	41..90		13/48 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	101..143		9/46 (20%)
		DKK-type Cys-2	145..218		7/15 (47%)
		Prokineticin	<145..202	CDD:148298	7/15 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1139517at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010