Protein Alignment spab and Dkk1

DIOPT Version :10

• Sequence 1: NP_610434.1
• Gene: spab / 35901
• FlyBaseID: FBgn0033358
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_034181.2
• Gene: Dkk1 / 13380
• MGIID: 1329040
• Length: 272
• Species: Mus musculus
• Alignment Length: 252
• Identity: 58/252 - (23%)
• Similarity: 82/252 - (32%)
• Gaps: 102/252 - (40%)

  Fly     6 RWAAMLLLLGLAHQLDPSLAASA---SSFASGNAWQRALFGRESRNLMHRRAPFSGAADLGLDEY 67
            |:.|:..::.|...  |.|.|||   |...:.||         .:||   ..|..||..
Mouse    11 RFLAVFTMMALCSL--PLLGASATLNSVLINSNA---------IKNL---PPPLGGAGG------ 55

  Fly    68 LGPYGAVE---------------QEQHQPHPPPQQMRQQTEVYGIVEPLIEDTPCADRPCLLNDD 117
             .|..||.               .:.:||:                 |..||..|.      :|:
Mouse    56 -QPGSAVSVAPGVLYEGGNKYQTLDNYQPY-----------------PCAEDEECG------SDE 96

  Fly   118 CC--PSGVCVSTYGEGKCVYVFGRQRDLCQGHADCPQGSSCMLVPQEGAWRCEPS---------- 170
            .|  ||.......|...|: ...::|..|..||.|..|:.|    :.|.  |.||
Mouse    97 YCSSPSRGAAGVGGVQICL-ACRKRRKRCMRHAMCCPGNYC----KNGI--CMPSDHSHFPRGEI 154

  Fly   171 ----VESGGS-------------TSLLEGIFGAKERQPLGSECSSSSDCQVINGMCC 210
                :|:.|:             |:|...|:..|.::  ||.|..||||..  |:||
Mouse   155 EESIIENLGNDHNAAAGDGYPRRTTLTSKIYHTKGQE--GSVCLRSSDCAA--GLCC 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spab	NP_610434.1	None
Dkk1	NP_034181.2	Dkk1_N_Cys1	16..142	CDD:438010	37/176 (21%)
		DKK-type Cys-1	86..141		17/67 (25%)
		Dkk1_Cys2	188..270	CDD:437998	11/24 (46%)
		DKK-type Cys-2	195..269		8/15 (53%)