Protein Alignment babo and acvr1

DIOPT Version :10

• Sequence 1: NP_476999.1
• Gene: babo / 35900
• FlyBaseID: FBgn0011300
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001017357.1
• Gene: acvr1 / 550111
• XenbaseID: XB-GENE-478850
• Length: 512
• Species: Xenopus tropicalis
• Alignment Length: 535
• Identity: 253/535 - (47%)
• Similarity: 336/535 - (62%)
• Gaps: 55/535 - (10%)

  Fly   111 LPIYI----AQPSAKKPENKI-----KCHCD--TCKESNNICETDGFCFTSVEKNSDGSIIFSYR 164
            |||.:    :.||.:..|.|:     ||.|:  :|...::.....  ||.|: .|:||.::....
 Frog     8 LPILMMVAFSSPSMEDEEMKLNAGQYKCVCEGMSCGSGDHCYGQQ--CFASL-SNNDGVLVSQKG 69

  Fly   165 CLHKSQIFPPGRSIWCNDGLHGGPTARPVGRNGAHACCKDRDFCNRFLWPKTKDQRSDRVEEGRQ 229
            |.   |::..|: :.|.         .|..::.|..||:. |.||..:..|..| .:.|.::|
 Frog    70 CF---QVYEQGK-MTCK---------TPPSQDQAVECCQS-DLCNMNITVKITD-LTGRTKQG-- 117

  Fly   230 ISVQDYVPHRLTSW----EFVAIILGATLFICFTGTSTWYYCQRRKRMASGRTFAKEDSAYDPIL 290
             ...:|....||.:    ..|.::|.....:.|....     ||..:|.|.|     |:.|..|.
 Frog   118 -EAPNYSVETLTIFILAPVIVLVVLSVLAVLIFRKIQ-----QRHMQMLSNR-----DAEYGTID 171

  Fly   291 N------GNTTIHDIIEMT-TSGSGSAGLPLLVQRSIARQVQLCHVIGKGRFGEVWRGRWRGENV 348
            .      |::|:.::::.: |||||| |||.||||::|||:.|...:||||:||||||.|:||:|
 Frog   172 GLIASNVGDSTLAEMLDHSCTSGSGS-GLPFLVQRTVARQITLAECVGKGRYGEVWRGLWQGESV 235

  Fly   349 AVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTT 413
            ||||||||:|.|||||.|:|.||:|||||||||||:|.....:.|||||:|.|||.|||:|||..
 Frog   236 AVKIFSSRDEKSWFRETELYNTVLLRHENILGFIASDMTSRNSSTQLWLITHYHELGSLYDYLQV 300

  Fly   414 HPVDTNTMLNMSLSIATGLAHLHMDIVGTRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHV 478
            ..:|:.|.|.:.||||:||||||::|.||:|||||:||||||||:|||.|..|.|.||||||.|.
 Frog   301 TTLDSVTCLRIVLSIASGLAHLHVEIFGTQGKPAISHRDLKSKNVLVKKNGQCCIADLGLAVMHS 365

  Fly   479 EKNDSVDIPSTHRVGTKRYMAPEVLDESMNDQHFDSYKRADVYAFGLILWEIARRCNMGMIYDEY 543
            :..:.:|:.:..|||||||||||||||::....||||||.|:|||||:|||:|||.....|.:||
 Frog   366 QTTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIYAFGLVLWEVARRMVSNGIVEEY 430

  Fly   544 QLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIK 608
            :.|:||||..|||.|:||||||:::.||||||||.:...|..:||:||||||.||.|||||||||
 Frog   431 KPPFYDVVPNDPSFEDMKKVVCVDQQRPNIPNRWFSDPTLTALAKLMKECWYQNPSARLTALRIK 495

  Fly   609 KTLASISVE-DKVKN 622
            |||..|... ||:|:
 Frog   496 KTLTKIDNSLDKLKS 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
babo	NP_476999.1	TFP_LU_ECD_Babo	127..210	CDD:467127	20/89 (22%)
		GS	294..324	CDD:197743	16/30 (53%)
		STKc_TGFbR1_ACVR1b_ACVR1c	328..615	CDD:271045	184/286 (64%)
acvr1	NP_001017357.1	TFP_LU_ECD_ALK2	33..103	CDD:467065	21/86 (24%)
		TGF_beta_GS	182..209	CDD:462503	14/27 (52%)
		STKc_ACVR1_ALK1	205..502	CDD:271044	189/296 (64%)